🏛️ Verified NIH Record • Updated 2026-08-27
A Study of Guselkumab in Participants With Active Psoriatic Arthritis (NCT04882098)
A Phase 3b, Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Subcutaneously Administered Guselkumab in Improving the Signs and Symptoms and Inhibiting Radiographic Progression in Participants With Active Psoriatic Arthritis
🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Janssen Research & Development, LLC
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to evaluate the efficacy of guselkumab treatment in participants with active psoriatic arthritis (PsA) by assessing the reduction in signs and symptoms of PsA.
Who can join: Review the eligibility criteria below.
Location: Rheumatology Associates — Birmingham, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (280 Sites)
Showing the first 25 of 280 sites.
- Rheumatology Associates — Birmingham, Alabama
- Arizona Arthritis and Rheumatology Research PLLC — Flagstaff, Arizona
- Arizona Arthritis & Rheumatology Associates PC — Glendale, Arizona
- Arizona Arthritis & Rheumatology Research, PLLC — Tucson, Arizona
- Advanced Medical Research — La Palma, California
- Rheumatology Center of San Diego — San Diego, California
- Medvin Clinical Research, Inc. — Whittier, California
- Heuer M.D. Research — Orlando, Florida
- The Arthritis Center, Inc. — Palm Harbor, Florida
- Forcare Clinical Research Inc — Tampa, Florida
- Klein And Associates M D P A — Hagerstown, Maryland
- Advanced Rheumatology — Okemos, Michigan
- Arthritis Consultants — St Louis, Missouri
- Glacier View Research Institute — Kalispell, Montana
- NYU Langone Ambulatory Care Brooklyn Heights — Brooklyn, New York
- PMG Research of Salisbury — Salisbury, North Carolina
- STAT Research, Inc. — Springboro, Ohio
- Altoona Center For Clinical Research — Duncansville, Pennsylvania
- Dr. Ramesh Gupta — Memphis, Tennessee
- Austin Regional Clinic — Austin, Texas
- Adriana Pop Moody MD Clinic PA — Corpus Christi, Texas
- Southwest Rheumatology Research LLC — Mesquite, Texas
- Arthritis And Osteoporosis Clinic — Waco, Texas
- The Queen Elizabeth Hospital — Adelaide,
- Southern Clinical Research — Hobart,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Arthritis, Psoriatic
- A Study of Guselkumab and Interleukin-17 (IL-17) Inhibitor Therapies in Participants With Psoriatic Arthritis in Routine Clinical Practice — Buenos Aires,
- Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis Naive to Biologic Disease-Modifying Antirheumatic Drug — Avondale, Arizona
- A Study to Evaluate the Efficacy and Safety of JNJ-77242113 (Icotrokinra) in Biologic-naïve Participants With Active Psoriatic Arthritis — Jonesboro, Arkansas
- A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease — Avondale, Arizona
- A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis — Glendale, Arizona
Explore by condition: All Arthritis, Psoriatic clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.