🏛️ Verified NIH Record • Updated 2026-08-27
A Study to Evaluate the Efficacy and Safety of JNJ-77242113 (Icotrokinra) in Biologic-naïve Participants With Active Psoriatic Arthritis (NCT06878404)
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of JNJ-77242113 for the Treatment of Biologic-naïve Participants With Active Psoriatic Arthritis
🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Janssen Research & Development, LLC
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to evaluate the efficacy of icotrokinra compared to placebo in participants with active psoriatic arthritis (PsA) by assessing the reduction in signs and symptoms of PsA.
Who can join: Review the eligibility criteria below.
Location: Arthritis and Rheumatism Associates ARA Jonesboro — Jonesboro, Arkansas
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (155 Sites)
Showing the first 25 of 155 sites.
- Arthritis and Rheumatism Associates ARA Jonesboro — Jonesboro, Arkansas
- Omega Research Consultants — DeBary, Florida
- Integral Rheumatology And Immunology Specialists — Plantation, Florida
- Clinical Research of West Florida — Tampa, Florida
- Willow Rheumatology and Wellness PLLC — Willowbrook, Illinois
- Joint and Muscle Research Institute — Charlotte, North Carolina
- Altoona Center For Clinical Research — Duncansville, Pennsylvania
- Arthritis and Rheumatology Research Institute — Allen, Texas
- Naiara Alvarez MD Integrative Rheumatology of South TX — Harlingen, Texas
- Cosultorios Reumatologógicos Pampa — Buenos Aires,
- Mindout Research — Buenos Aires,
- Hospital Central Militar Cirujano Mayor Dr Cosme Argerich — Buenos Aires,
- Arsema — Ciudad de Buenos Aires,
- Centro Medico Privado de Reumatologia Tucuman — Ciudad de San Miguel de Tucuman,
- Consultora Integral de Salud SRL — Córdoba,
- MR Medicina Reumatologica — San Fernando,
- Instituto Medico De Alta Complejidad (IMAC) — San Isidro,
- Ipswich Hospital — Ipswich,
- Rheumatology Research Unit — Maroochydore,
- BJC Health — Parramatta,
- Queen Elizabeth Hospital — South Woodville,
- Royal Darwin Hospital — Tiwi,
- MC Medtech Services Ltd — Haskovo,
- Exacta Medica — Pleven,
- Medical Center Artmed — Plovdiv,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Arthritis, Psoriatic
- A Study of Guselkumab and Interleukin-17 (IL-17) Inhibitor Therapies in Participants With Psoriatic Arthritis in Routine Clinical Practice — Buenos Aires,
- Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis Naive to Biologic Disease-Modifying Antirheumatic Drug — Avondale, Arizona
- A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease — Avondale, Arizona
- A Study of Guselkumab in Participants With Active Psoriatic Arthritis — Birmingham, Alabama
- A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis — Glendale, Arizona
Explore by condition: All Arthritis, Psoriatic clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.