🏛️ Verified NIH Record • Updated 2026-05-22

Combination Cefazolin With Ertapenem for Methicillin-susceptible Staphylococcus Aureus Bacteremia (NCT04886284)

Combination Cefazolin With Ertapenem for Methicillin-susceptible Staphylococcus Aureus Bacteremia (CERT)

🟢 Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Todd C. Lee MD MPH FIDSA

🩺 Plain-English Summary (8th-Grade Level)

There is a variety of in vitro, in vivo (animal model), and human case series data which suggests that the addition of ertapenem to cefazolin could improve outcomes in methicillin-susceptible S. aureus bacteremia. No randomized controlled trial has been performed. This study is an approved sub-study of The Staphylococcus aureus Network Adaptive Platform (SNAP) trial (NCT05137119)

Who can join: Review the eligibility criteria below.

Location: Foothills Medical Centre — Calgary, Alberta

Age range: 18 Years to 100 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (6 Sites)

  • Foothills Medical Centre — Calgary, Alberta
  • Hamilton Health Sciences (Hamilton General Hospital and Juravinski Hospital) — Hamilton, Ontario
  • Niagara Health - St. Catharines site — Saint Catharines, Ontario
  • Hospital de la Cité de la Sante — Laval, Quebec
  • Jewish General Hospital — Montreal, Quebec
  • McGill University Health Centre (Royal Victoria Hospital and Montreal General Hospital) — Montreal, Quebec

📞 Contact the Study Coordinator

Phone: (514) 934-1934

Email: lina.petrella@muhc.mcgill.ca

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗