Adjunctive Fosfomycin for Treatment of Staphylococcus Aureus Bacteraemia (NCT06695832)
Adjunctive Fosfomycin for Treatment of Staphylococcus Aureus Bacteraemia: Protocol for a Pooled Post-hoc Analysis of Two Randomised Clinical Trials
🩺 Plain-English Summary (8th-Grade Level)
Staphylococcus aureus bacteraemia is a frequent and life-threatening infection, despite current standard antibiotic monotherapy. This study aims to clarify the role of fosfomycin as an adjunctive therapy for improving outcomes in patients with this serious infection. Two clinical trials suggested that adjunctive fosfomycin therapy might offer a clinical benefit in certain cases, but the results are inconclusive. We aim to analyse pooled data from these trials in order to identify subgroups of patients that might benefit most from this therapy.
Who can join: Review the eligibility criteria below.
Location: The Royal Melbourne Hospital, at the Peter Doherty Institute for Infection and Immunity — Melbourne, Victoria
Age range: 18 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (6 Sites)
- The Royal Melbourne Hospital, at the Peter Doherty Institute for Infection and Immunity — Melbourne, Victoria
- Institute of Health Policy, Management and Evaluation, University of Toronto — Toronto, Ontario
- Hospital Universitari de Bellvitge — L'Hospitalet de Llobregat, Barcelona
- Germans Trias i Pujol Research Institute and Hospital (IGTP) — Badalona, Catalonia
- Hospital Clinic de Barcelona — Barcelona, Catalonia
- Hospital de la Santa Creu i Sant Pau — Barcelona, Catalonia
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Staphylococcus Aureus Bacteremia
- Combination Cefazolin With Ertapenem for Methicillin-susceptible Staphylococcus Aureus Bacteremia — Calgary, Alberta
- Staphylococcus Aureus Network Adaptive Platform Trial — Houston, Texas
- Evaluating Simplified Layered Consent for Clinical Trials — Calgary, Alberta
- Combination Antibiotic Therapy for Staphylococcus Aureus Bacteremia — Brighton, Colorado
Explore by condition: All Staphylococcus Aureus Bacteremia clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.