Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D) (NCT05017311)
🩺 Plain-English Summary (8th-Grade Level)
This is a study that will test a predictive biomarker algorithm based on results from a previous study. The goal of this study is to integrate clinical, imaging, EEG, and molecular data across 8 sites to predict treatment outcome for patients experiencing a major depressive episode (MDE).
Who can join: Review the eligibility criteria below.
Location: University of Calgary — Calgary, Alberta
Age range: 18 Years to 65 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (10 Sites)
- University of Calgary — Calgary, Alberta
- University of British Columbia — Vancouver, British Columbia
- Nova Scotia Health Authority — Halifax, Nova Scotia
- McMaster University — Hamilton, Ontario
- Queen's University — Kingston, Ontario
- The Royal Ottawa Mental Health Centre — Ottawa, Ontario
- University Health Network — Toronto, Ontario
- Centre for Addiction and Mental Health — Toronto, Ontario
- Ontario Shores Centre for Mental Health Sciences — Whitby, Ontario
- University of Saskatchewan — Saskatoon, Saskatchewan
📞 Contact the Study Coordinator
Phone: (902) 473-5313
Email: Jessica.Toombs@NSHealth.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Major Depressive Disorder
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- Effects of Intravenous (IV) Citalopram Hydrochloride During Transcranial Magnetic Stimulation in Major Depressive Disorder (MDD) — Los Angeles, California
- Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: Comparing One Versus Two Doses of Psilocybin — Toronto, Ontario
- Psilocybin - Induced Neuroplasticity in the Treatment of Major Depressive Disorder — West Haven, Connecticut
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Explore by condition: All Major Depressive Disorder clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.