🏛️ Verified NIH Record • Updated 2026-08-10
Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease (NCT05099770)
A Phase 3 Randomized Controlled Study of Renal Autologous Cell Therapy (REACT) in Subjects With Type 2 Diabetes and Chronic Kidney Disease (REGEN-006)
🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Prokidney
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to assess the safety and efficacy of up to 2 REACT/rilparencel injections in participants with T2DM and CKD.
Who can join: Review the eligibility criteria below.
Location: Nephrology Consultants — Huntsville, Alabama
Age range: 30 Years to 80 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (88 Sites)
Showing the first 25 of 88 sites.
- Nephrology Consultants — Huntsville, Alabama
- University of Arizona — Tucson, Arizona
- Amicis Research Center — Beverly Hills, California
- Kidney Consultants Medical Group — Granada Hills, California
- IMD Clinical Trials — Huntington Park, California
- Advanced Medical Research, LLC — Lakewood, California
- Medicine and Nephrology Associates — Los Alamitos, California
- Academic Medical Research Institute — Los Angeles, California
- Southern California Hospital — Los Angeles, California
- Allameh Medical Corporation — Mission Viejo, California
- Golden Pacific Nephrology Medical Clinic Inc — Monterey Park, California
- Northridge Kidney Care Center — Northridge, California
- Valley Renal Medical Group — Northridge, California
- Valley Clinical Trials — Northridge, California
- Integrity Medical Discovery — Pico Rivera, California
- National Institute of Clinical Research — Pomona, California
- Nephrology Associates Medical Group — Riverside, California
- UC Davis Medical Group GI Unit — Sacramento, California
- North America Research Institute — San Dimas, California
- Henry Mayo Newhall Hospital — Valencia, California
- Nephrology Associates PA — Newark, Delaware
- West Broward Research Institute — Coral Springs, Florida
- Florida Kidney Physicians — Fort Lauderdale, Florida
- South Fort Lauderdale Nephrology — Fort Lauderdale, Florida
- University of Florida — Gainesville, Florida
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Type 2 Diabetes Mellitus
- Renal HEIR Study: Renal Hemodynamics, Energetics and Insulin Resistance in Youth Onset Type 2 Diabetes Study — Aurora, Colorado
- A Study to Compare Different Doses of RO7795081 With a Placebo or Semaglutide in People With Type 2 Diabetes — Tucson, Arizona
- Preventing Type 2 Diabetes in Black Emergent Adult — Chapel Hill, North Carolina
- Safety and Effectiveness of Endoscopic Intestinal Re-Cellularization Therapy in Individuals With Type II Diabetes — Birmingham, Alabama
- GLP-1 and Hypoglycemia — Baltimore, Maryland
Explore by condition: All Type 2 Diabetes Mellitus clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.