A Study to Compare Different Doses of RO7795081 With a Placebo or Semaglutide in People With Type 2 Diabetes (NCT07112872)
A Randomized, Double-Blind, Placebo- and Open-Label Active Comparator- Controlled, Parallel-Group, Multi-Center Phase II Study to Evaluate the Efficacy, Safety, and Tolerability of Once-Daily RO7795081 Administered for 30 Weeks to Participants With Type 2 Diabetes Mellitus
🩺 Plain-English Summary (8th-Grade Level)
This multicenter, randomized, double-blind, placebo- and open-label active comparator-controlled, parallel-group, dose-range-finding, Phase II study aims to evaluate the efficacy, tolerability, and safety of RO7795081 for glycemic control in adult participants with Type 2 diabetes mellitus (T2D).
Who can join: Review the eligibility criteria below.
Location: Arizona Liver Health - Tucson — Tucson, Arizona
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (50 Sites)
Showing the first 25 of 50 sites.
- Arizona Liver Health - Tucson — Tucson, Arizona
- Orange County Research Center — Lake Forest, California
- Prospective Research Innovations Inc. — Rancho Cucamonga, California
- Encompass Clinical Research — Spring Valley, California
- Chase Medical Research — Waterbury, Connecticut
- Emerson Clinical Research Institute — Washington D.C., District of Columbia
- K2 Medical Research South Orlando, LLC — Clermont, Florida
- Center for Diabetes, Obesity and Metabolism Inc — Pembroke Pines, Florida
- Rophe Adult and Pediatric Medicine/SKYCRNG — Union City, Georgia
- Accellacare of Duly Health and Care — Oak Lawn, Illinois
- Mercury Street Medical Group, PLLC — Butte, Montana
- Neurobehavioral Research, Inc. — Cedarhurst, New York
- Accellacare of Piedmont Healthcare — Statesville, North Carolina
- Accellacare of Wilmington, LLC — Wilmington, North Carolina
- NexGen Research — Lima, Ohio
- Tristar Clinical Investigations — Philadelphia, Pennsylvania
- Alliance for Multispecialty Research. LLC — Knoxville, Tennessee
- Clinical Research Associates — Nashville, Tennessee
- Texas Diabetes & Endocrinology, P.A. — Austin, Texas
- Apex Mobile Clinical Research — Bellaire, Texas
- Velocity Clinical Research — Dallas, Texas
- Velocity Clinical Research (Impact Research Institute) — Waco, Texas
- Chrysalis Clinical Research — St. George, Utah
- Manassas Clinical Research Center — Manassas, Virginia
- Obudai Egeszsegugyi Centrum Kft. — Budapest,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Type 2 Diabetes Mellitus
- Renal HEIR Study: Renal Hemodynamics, Energetics and Insulin Resistance in Youth Onset Type 2 Diabetes Study — Aurora, Colorado
- Preventing Type 2 Diabetes in Black Emergent Adult — Chapel Hill, North Carolina
- Safety and Effectiveness of Endoscopic Intestinal Re-Cellularization Therapy in Individuals With Type II Diabetes — Birmingham, Alabama
- Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease — Huntsville, Alabama
- GLP-1 and Hypoglycemia — Baltimore, Maryland
Explore by condition: All Type 2 Diabetes Mellitus clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.