Connectomic Deep Brain Stimulation for Obsessive Compulsive Disorder (NCT05160129)
🩺 Plain-English Summary (8th-Grade Level)
Deep brain stimulation (DBS) is an effective treatment for people suffering from severe obsessive-compulsive disorder (OCD) whose symptoms have failed to improve after years and multiple methods of intervention. An effective DBS target for OCD is the anterior limb of the internal capsule (ALIC) brain region. On average 60% of all OCD patients have a clinically significant response to ALIC DBS. However, ALIC DBS may become even more effective with the ability to predict which specific ALIC connections in the brain need to be stimulated for each individual OCD patient. This study therefore investigates personalized stimulation to the ALIC that allows for precise modulation of brain circuits associated with individual OCD symptoms. The study aims to specify the ideal anatomical target for ALIC DBS for maximum therapeutic benefit in each patient.
Who can join: Review the eligibility criteria below.
Location: Mount Sinai West — New York, New York
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Mount Sinai West — New York, New York
📞 Contact the Study Coordinator
Phone: (212) 523-8279
Email: abigeal.kiros@mssm.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Obsessive Compulsive Disorder (OCD)
- Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children and Adolescents With Anxiety and OCD — Houston, Texas
- Priming CBT With rTMS for OCD — Toronto, Ontario
- Brain-Oscillation Synchronized Stimulation of the DMPFC — Toronto, Ontario
- ERP to Improve Functioning in Veterans With OCD — East Orange, New Jersey
- Neurophysiological Investigation of the Approach-avoidance Axis in OCD: Applications to Neuromodulation — Houston, Texas
Explore by condition: All Obsessive Compulsive Disorder (OCD) clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.