ERP to Improve Functioning in Veterans With OCD (NCT05240924)
Exposure and Response Prevention to Improve Functioning in Veterans With Obsessive Compulsive Disorder
🩺 Plain-English Summary (8th-Grade Level)
Obsessive compulsive disorder (OCD) is a debilitating psychiatric illness impacting work, social, and family functioning. Exposure and Response Prevention (ERP) is the sole evidence-based psychotherapy for OCD; however, no randomized controlled trials (RCTs) have examined the effectiveness of ERP among Veterans or individuals with both OCD and posttraumatic stress disorder (PTSD). This 4-year Hybrid Type I trial will compare outcomes of ERP to those of a control condition among Veterans with OCD. Primary and secondary aims will examine whether Veterans' functioning, quality of life, and OCD symptoms differ between the ERP and control in the full sample of Veterans with OCD, and in the half of the sample with both OCD and PTSD. The tertiary aim is to conduct a mixed-methods formative evaluation of the implementation potential of ERP in VA mental health settings.
Who can join: Review the eligibility criteria below.
Location: East Orange Campus of the VA New Jersey Health Care System, East Orange, NJ — East Orange, New Jersey
Age range: 18 Years
🧪 Interventions in This Study
- Exposure and Response Prevention (BEHAVIORAL)
- Stress Management Training (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (19 Sites)
- East Orange Campus of the VA New Jersey Health Care System, East Orange, NJ — East Orange, New Jersey
- VA Western New York Healthcare System, Buffalo, NY — Buffalo, New York
- VA NY Harbor Healthcare System, New York, NY — New York, New York
- Northport VA Medical Center, Northport, NY — Northport, New York
- James J. Peters VA Medical Center, Bronx, NY — The Bronx, New York
- Asheville VA Medical Center, Asheville, NC — Asheville, North Carolina
- Durham VA Medical Center, Durham, NC — Durham, North Carolina
- Fayetteville VA Medical Center, Fayetteville, NC — Fayetteville, North Carolina
- Salisbury W.G. (Bill) Hefner VA Medical Center, Salisbury, NC — Salisbury, North Carolina
- VA Roseburg Healthcare System, Roseburg, OR — Roseburg, Oregon
- VA Southern Oregon Rehabilitation Center and Clinics, White City, OR — White City, Oregon
- Ralph H. Johnson VA Medical Center, Charleston, SC — Charleston, South Carolina
- Michael E. DeBakey VA Medical Center, Houston, TX — Houston, Texas
- Michael E. DeBakey VA Medical Center, Houston, TX — Houston, Texas
- Hampton VA Medical Center, Hampton, VA — Hampton, Virginia
- Hunter Holmes McGuire VA Medical Center, Richmond, VA — Richmond, Virginia
- Salem VA Medical Center, Salem, VA — Salem, Virginia
- Spokane VA Medical Center, Spokane, WA — Spokane, Washington
- Jonathan M. Wainwright Memorial VA Medical Center, Walla Walla, WA — Walla Walla, Washington
📞 Contact the Study Coordinator
Phone: (713) 440-4400
Email: Terri.Fletcher@va.gov
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Obsessive Compulsive Disorder (OCD)
- Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children and Adolescents With Anxiety and OCD — Houston, Texas
- Priming CBT With rTMS for OCD — Toronto, Ontario
- Brain-Oscillation Synchronized Stimulation of the DMPFC — Toronto, Ontario
- Connectomic Deep Brain Stimulation for Obsessive Compulsive Disorder — New York, New York
- Neurophysiological Investigation of the Approach-avoidance Axis in OCD: Applications to Neuromodulation — Houston, Texas
Explore by condition: All Obsessive Compulsive Disorder (OCD) clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.