A Global Clinical Study Investigating the Safety and Effectiveness of Smith and Nephew's Porous Knee System in Patients Who Need a Total Knee Replacement Due to Degenerative Arthritis, Post-traumatic Arthritis or Inflammatory Arthritis (NCT05197036)
A Multi-Centre Study in Patients Undergoing Total Knee Replacement With Smith+Nephew Porous Total Knee Arthroplasty (TKA) System
🩺 Plain-English Summary (8th-Grade Level)
A clinical trial investigating the safety and effectiveness of Smith and Nephew's FDA-approved Porous Total Knee System, which is used to replace worn away and diseased knee joints. The aim of this study is to show that most patients who receive the Porous Total Knee System have reduced pain, greater mobility and a long-lasting implant post-surgery.
Who can join: Review the eligibility criteria below.
Location: Emory Orthopaedics and Spine Hospital — Atlanta, Georgia
Age range: 18 Years to 80 Years
🧪 Interventions in This Study
- Total Knee Arthroplasty (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (18 Sites)
- Emory Orthopaedics and Spine Hospital — Atlanta, Georgia
- Massachusetts General Hospital — Boston, Massachusetts
- The Core Institute — Novi, Michigan
- Syracuse Orthopedic Specialists — East Syracuse, New York
- NYU Langone Health Orthopedic Hospital — New York, New York
- Columbia University — New York, New York
- Duke Health — Morrisville, North Carolina
- Oregon Health & Science University — Portland, Oregon
- Medical University of South Carolina — Charleston, South Carolina
- Erlanger Health — Chattanooga, Tennessee
- UTHealth — Houston, Texas
- University of Wisconsin — Madison, Wisconsin
- St George and Sutherland Centre for Clinical Orthopaedic Research — Sydney, New South Wales
- The Avenue Hospital — Windsor, Victoria
- Concordia Joint Replacement Group — Winnipeg, Manitoba
- Medical Center Leeuwarden — Leeuwarden, Leeuwarden
- Sint Maartenskliniek — Ubbergen, Ubbergen,
- Umeå University Hospital — Umeå, Umeå
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.