The PATHway Study: Primary Care Based Depression Prevention in Adolescents (NCT05203198)
Primary Care Based Depression Prevention in Adolescents: Intervention Optimization in Preparation for Implementation Study
🩺 Plain-English Summary (8th-Grade Level)
Prevention of depressive disorders has become a key priority for the NIMH, but the investigators have no widely available public health strategy to reduce morbidity and mortality. To address this need, the investigators developed and evaluated the primary care based-technology "behavioral vaccine," Competent Adulthood Transition with Cognitive-Behavioral Humanistic and Interpersonal Therapy (CATCH-IT). The investigators will engage N=4 health systems representative of the United States health care system, and conduct a factorial design study to optimize the intervention in preparation for an implementation study and eventual dissemination.
Who can join: Review the eligibility criteria below.
Location: Ann & Robert H. Lurie Children's Hospital of Chicago — Chicago, Illinois
Age range: 13 Years to 18 Years
🧪 Interventions in This Study
- Competent Adulthood Transition with Cognitive-Behavioral, Humanistic and Interpersonal Training (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (6 Sites)
- Ann & Robert H. Lurie Children's Hospital of Chicago — Chicago, Illinois
- UI Health — Chicago, Illinois
- University of Chicago Comer Children's Hospital — Chicago, Illinois
- Northshore University HealthSystem — Glenview, Illinois
- Advocate Aurora Health — Park Ridge, Illinois
- UT Southwestern Medical Center — Dallas, Texas
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Depression
- Neural Circuit Biomarkers of Transcranial Magnetic Stimulation Study — Stanford, California
- Meditation Accelerated Brain Stimulation for Depression — San Diego, California
- A Behavioral Activation Prenatal and Postpartum Intervention for Depressed Pregnant Smokers — Houston, Texas
- EEG Biomarker Study for Participants in the Neurolief "MOOD" Trial — Providence, Rhode Island
- Using rTMS to Treat Depression — Miami, Florida
- Integrating Ketamine Effects on Neuronal Molecular Signatures and the Brain Functional and Structural Connectome — Boston, Massachusetts
Explore by condition: All Depression clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.