Piromelatine 20 mg in Participants With Mild Dementia Due to Alzheimer's Disease (NCT05267535)
Randomized, Delayed Start, Double Blind, Parallel Group, Placebo Controlled, Multicenter Study of Piromelatine 20 mg in Participants With Mild Dementia Due to Alzheimer's Disease
🩺 Plain-English Summary (8th-Grade Level)
Randomized efficacy and safety study of piromelatine 20 mg versus placebo in participants with mild dementia due to Alzheimer's disease (AD) who are 2:107,510,000-107,540,000 polymorphism non-carriers with the primary objective to compare the effect of piromelatine to that of placebo on the AD Assessment Scale cognitive subscale (ADAS-cog14) at Week 26 of double-blind treatment.
Who can join: Review the eligibility criteria below.
Location: ATP Clinical Research — Costa Mesa, California
Age range: 60 Years to 85 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (37 Sites)
Showing the first 25 of 37 sites.
- ATP Clinical Research — Costa Mesa, California
- Collaborative Neuroscience Research, LLC — Long Beach, California
- Asclepes Research Centers, P.C. Dba Alliance Research — Long Beach, California
- Pacific Research Network, LLC — San Diego, California
- RAA Apex Acquisition LLC DBA Syrentis Clinical Research — Santa Ana, California
- The Mile High Research Center — Denver, Colorado
- Linfritz Research Institute Inc. — Coral Gables, Florida
- Finlay Medical Research Corp. — Greenacres City, Florida
- Velocity Clinical Research, Inc — Hallandale, Florida
- K2 Medical Research The Villages — Lady Lake, Florida
- Verus Clinical research Corp — Miami, Florida
- BioMed Research Institute, Inc. — Miami, Florida
- CCM Clinical Research Group, LLC — Miami, Florida
- Advance Medical Research Center — Miami, Florida
- Allied Biomedical Research Institute (Clinical Trials) — Miami, Florida
- Vitae Research Center LLC. — Miami, Florida
- Stein Gerontological Institute, Inc. — Miami, Florida
- Miami Dade Medical Research Institute — Miami, Florida
- K2 Medical Research Winter Garden — Ocoee, Florida
- Interspond, LLC, — Orlando, Florida
- The University of South Florida Board of Trustees, — Tampa, Florida
- Alzheimer's Research and Treatment Center — Wellington, Florida
- Velocity Clinical Research, Inc — Meridian, Idaho
- Ocean Medical Research — Jersey City, New Jersey
- Advanced Memory Research Institute of New Jersey — Toms River, New Jersey
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.