Descemet Endothelial Thickness Comparison Trial I (NCT05289661)
Descemet Endothelial Thickness Comparison Trials (DETECT I & II)
🩺 Plain-English Summary (8th-Grade Level)
Descemet Endothelial Thickness Comparison Trial (DETECT) I is a multi-center, outcome assessor-masked, placebo-controlled clinical trial randomizing 160 patients in a 2x2 factorial design. The purpose of this study is to determine differences in visual outcomes between two types of corneal transplant surgeries, ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) and Descemet membrane endothelial keratoplasty (DMEK), and to determine the effect of rho-kinase inhibitors on endothelial cell loss.
Who can join: Review the eligibility criteria below.
Location: Stanford University — Palo Alto, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (7 Sites)
- Stanford University — Palo Alto, California
- University of California Davis — Sacramento, California
- University of Miami — Palm Beach Gardens, Florida
- Dartmouth-Hitchcock Medical Center — Lebanon, New Hampshire
- Oregon Health & Science University — Portland, Oregon
- University of Pennsylvania — Philadelphia, Pennsylvania
- Wills Eye Hospital — Philadelphia, Pennsylvania
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Fuchs
- Descemet Endothelial Thickness Comparison Trial II — Palo Alto, California
Explore by condition: All Fuchs clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.