๐๏ธ Verified NIH Record โข Updated 2026-01-16
Prevention of Asthma Exacerbations Using Dupilumab in Urban Children and Adolescents (NCT05347771)
Prevention of Asthma Exacerbations Using Dupilumab in Urban Children and Adolescents (PANDA) (CAUSE-01)
๐ต Active, Not Recruiting Phase2 ๐ Investigational Drug / Biologic Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
๐ฉบ Plain-English Summary (8th-Grade Level)
This is a multi-center, double-blind, placebo-controlled, randomized trial of dupilumab adjunctive therapy for prevention of asthma exacerbations in urban children and adolescents with T2-high exacerbation-prone asthma.
Who can join: Review the eligibility criteria below.
Location: Children's Hospital Colorado: Allergy Program โ Aurora, Colorado
Age range: 6 Years to 17 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (8 Sites)
- Children's Hospital Colorado: Allergy Program โ Aurora, Colorado
- Children's National Medical Center: Children's Research Institute โ Washington D.C., District of Columbia
- Ann & Robert H. Lurie Children's Hospital of Chicago: Division of Allergy and Immunology โ Chicago, Illinois
- Boston Children's Hospital: Department of Immunology โ Boston, Massachusetts
- Washington University at St. Louis โ St Louis, Missouri
- Icahn School of Medicine at Mount Sinai: Division of Clinical Immunology, Immunology Institute โ New York, New York
- Columbia University Medical Center: Division of Pediatric Pulmonology โ New York, New York
- Cincinnati Children's Hospital Medical Center: Asthma Center โ Cincinnati, Ohio
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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Explore by condition: All Asthma clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.