๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-01-16

Prevention of Asthma Exacerbations Using Dupilumab in Urban Children and Adolescents (NCT05347771)

Prevention of Asthma Exacerbations Using Dupilumab in Urban Children and Adolescents (PANDA) (CAUSE-01)

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a multi-center, double-blind, placebo-controlled, randomized trial of dupilumab adjunctive therapy for prevention of asthma exacerbations in urban children and adolescents with T2-high exacerbation-prone asthma.

Who can join: Review the eligibility criteria below.

Location: Children's Hospital Colorado: Allergy Program โ€” Aurora, Colorado

Age range: 6 Years to 17 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (8 Sites)

  • Children's Hospital Colorado: Allergy Program โ€” Aurora, Colorado
  • Children's National Medical Center: Children's Research Institute โ€” Washington D.C., District of Columbia
  • Ann & Robert H. Lurie Children's Hospital of Chicago: Division of Allergy and Immunology โ€” Chicago, Illinois
  • Boston Children's Hospital: Department of Immunology โ€” Boston, Massachusetts
  • Washington University at St. Louis โ€” St Louis, Missouri
  • Icahn School of Medicine at Mount Sinai: Division of Clinical Immunology, Immunology Institute โ€” New York, New York
  • Columbia University Medical Center: Division of Pediatric Pulmonology โ€” New York, New York
  • Cincinnati Children's Hospital Medical Center: Asthma Center โ€” Cincinnati, Ohio

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Asthma clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—