🏛️ Verified NIH Record • Updated 2026-03-20
Colorectal Cancer Screening in Cystic Fibrosis (NCT05362344)
A Multi-Center Study of Non-Invasive Colorectal Cancer Evaluation in Cystic Fibrosis (NICE-CF)
🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: University of Washington, the Collaborative Health Studies Coordinating Center
🩺 Plain-English Summary (8th-Grade Level)
This multi-center study will compare multi-target DNA and quantitative FIT stool-based testing to colonoscopy in individuals with Cystic Fibrosis (CF) undergoing colon cancer screening with colonoscopy. The primary endpoint is detection of any adenomas, including advanced adenomas and colorectal cancer (CRC).
Who can join: Review the eligibility criteria below.
Location: University of California, Los Angeles — Los Angeles, California
Age range: 18 Years to 75 Years
🧪 Interventions in This Study
- Stool tests (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (26 Sites)
Showing the first 25 of 26 sites.
- University of California, Los Angeles — Los Angeles, California
- Stanford University Medical Center — Palo Alto, California
- National Jewish Health, University of Colorado — Denver, Colorado
- University of Miami Hospital — Miami, Florida
- University of Kansas Medical Center — Kansas City, Kansas
- Johns Hopkins Hospital, Johns Hopkins University — Baltimore, Maryland
- Massachusetts General Hospital — Boston, Massachusetts
- Boston Children's Hospital — Boston, Massachusetts
- Michigan Medicine - University of Michigan — Ann Arbor, Michigan
- University of Minnesota — Minneapolis, Minnesota
- Saint Louis University — St Louis, Missouri
- Washington University — St Louis, Missouri
- Columbia University Medical Center — New York, New York
- North Carolina Children's Hospital / UNC — Chapel Hill, North Carolina
- Atrium Health Pulmonary Care — Charlotte, North Carolina
- University Hospitals Rainbow Babies & Children's — Cleveland, Ohio
- Nationwide Children's Hospital — Columbus, Ohio
- Oregon Health & Science University — Portland, Oregon
- Hospital of the University of Pennsylvania — Philadelphia, Pennsylvania
- University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania
- Medical University of South Carolina — Charleston, South Carolina
- Vanderbilt University Medical Center — Nashville, Tennessee
- University of Texas Southwestern — Dallas, Texas
- University of Utah — Salt Lake City, Utah
- University of Washington — Seattle, Washington
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cystic Fibrosis
- Genetic Modifiers of Cystic Fibrosis (CF) Liver Disease — Chapel Hill, North Carolina
- Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age — Orange, California
- Hyperpolarized Imaging for New Treatments — Cincinnati, Ohio
- Monitoring Response to Orkambi in Cystic Fibrosis Lung Disease by Inhaled Xenon MRI — Cincinnati, Ohio
- Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis Participants 12 Months of Age and Older — Nedlands,
- Non-contrast Lung Perfusion Mapping Applied for New Insights in Cystic Fibrosis — Cincinnati, Ohio
Explore by condition: All Cystic Fibrosis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.