Tourette Deep Brain Stimulation (DBS) Target Detection & Suppression (NCT05371041)
Defining Targets for Tic Detection and Suppression in Tourette Syndrome Deep Brain Stimulation
🩺 Plain-English Summary (8th-Grade Level)
The investigators will implant and monitor 8 research subjects with a subcortical closed-loop system for detection and suppression of tics in subjects with medically refractory debilitating Tourette Syndrome. The project will use the FDA-approved "Medtronic Percept PC" device, which is an implantable neurostimulator capable of recording neural signals. The study will target the CM nucleus of the thalamus and the aGPi in each brain hemisphere from each subject and we will connect the two leads placed in each brain hemisphere to two Percept devices.
Who can join: Review the eligibility criteria below.
Location: Norman Fixel Institute for Neurological Diseases - University of Florida — Gainesville, Florida
Age range: 18 Years to 85 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Norman Fixel Institute for Neurological Diseases - University of Florida — Gainesville, Florida
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Tourette Syndrome
- Efficacy and Safety of Gemlapodect (NOE-105) in Adults and Adolescents With Tourette Syndrome — Sun City, Arizona
- A Study to Evaluate Long-term Safety of Ecopipam Tablets in Children, Adolescents and Adults With Tourette's Disorder — Dothan, Alabama
- SCI-110 in the Treatment of Tourette Syndrome — New Haven, Connecticut
- Trajectories of Change in Tourette Syndrome — Minneapolis, Minnesota
- Sensory Symptoms in Tourette Syndrome — Nashville, Tennessee
Explore by condition: All Tourette Syndrome clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.