🏛️ Verified NIH Record • Updated 2026-03-05
Efficacy and Safety of Gemlapodect (NOE-105) in Adults and Adolescents With Tourette Syndrome (NCT06315751)
A Double-blind, Placebo-controlled, Phase 2b, Multi-center, Twelve-week Prospective Study to Evaluate the Efficacy and Safety of Gemlapodect in Adult and Adolescent Patients With Tourette Syndrome
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Noema Pharma AG
🩺 Plain-English Summary (8th-Grade Level)
This study is designed to evaluate the efficacy and safety of gemlapodect (NOE-105) on reducing tics associated with Tourette Syndrome (TS) in adults with TS. Adolescents will be enrolled after a sentinel cohort of adults is complete.
Who can join: Review the eligibility criteria below.
Location: Noema TTS-201 Site #81 — Sun City, Arizona
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (46 Sites)
Showing the first 25 of 46 sites.
- Noema TTS-201 Site #81 — Sun City, Arizona
- Noema TTS-201 Site #95 — Bellflower, California
- Noema TTS-201 Site #75 — Glendale, California
- Noema TTS-201 Site #59 — San Rafael, California
- Noema TTS-201 Site #21 — Walnut Creek, California
- Noema TTS-201 Site #54 — Gulf Breeze, Florida
- Noema TTS-201 Site #05 — Hialeah, Florida
- Noema TTS-201 Site #97 — Jensen Beach, Florida
- Noema TTS-201 Site #71 — Largo, Florida
- Noema TTS-201 Site #44 — Maitland, Florida
- Noema TTS-201 Site # 74 — Miami, Florida
- Noema TTS-201 Site #56 — Miami Lakes, Florida
- Noema TTS-201 Site #61 — Orlando, Florida
- Noema TTS-201 Site #79 — Atlanta, Georgia
- Noema TTS-201 Site #87 — Peachtree Corners, Georgia
- Noema TTS-201 Site #55 — Boston, Massachusetts
- Noema TTS-201 Site #51 — Ann Arbor, Michigan
- Noema TTS-201 Site #96 — Saint Charles, Missouri
- Noema TTS-201 Site #93 — Lincoln, Nebraska
- NOema TTS-201 Site #19 — New York, New York
- Noema TTS-201 Site #03 — Stony Brook, New York
- Noema TTS-201 Site #57 — Charlotte, North Carolina
- Noema TTS-201 Site #58 — Middleburg Heights, Ohio
- Noema TTS-201 Site #73 — North Charleston, South Carolina
- Noema TTS-201 Site #98 — Nashville, Tennessee
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Tourette Syndrome
- A Study to Evaluate Long-term Safety of Ecopipam Tablets in Children, Adolescents and Adults With Tourette's Disorder — Dothan, Alabama
- Tourette Deep Brain Stimulation (DBS) Target Detection & Suppression — Gainesville, Florida
- SCI-110 in the Treatment of Tourette Syndrome — New Haven, Connecticut
- Trajectories of Change in Tourette Syndrome — Minneapolis, Minnesota
- Sensory Symptoms in Tourette Syndrome — Nashville, Tennessee
Explore by condition: All Tourette Syndrome clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.