Effect of Hypercapnia Treatment on Respiratory Recovery After Spinal Cord Injury (NCT05536076)
🩺 Plain-English Summary (8th-Grade Level)
It is estimated that 1,275,000 people in the United States alone live with spinal cord injury, including around 100,000 Veterans with spinal cord injury, making the V.A. the largest integrated health care system in the world for spinal cord injuries injury care. New therapies are needed to prevent the morbidities and mortalities associated with the high prevalence of respiratory disorders in Veterans with spinal cord injury. The current research project and future studies would set the base for developing innovative therapies for this disorder. This proposal addresses a new therapeutic intervention for sleep apnea in spinal cord injury. The investigators hypothesized that daily hypercapnia treatments improve respiratory symptoms and alleviate sleep apnea in patients with chronic spinal cord injury. The investigators will perform a pilot study to examine the impact of daily hypercapnia treatments for-two week durations among Veterans with spinal cord injury. The investigators believe that this novel approach to treating sleep apnea and will yield significant new knowledge that improves the health and quality of life of these patients.
Who can join: Review the eligibility criteria below.
Location: John D. Dingell VA Medical Center, Detroit, MI — Detroit, Michigan
Age range: 18 Years to 89 Years
🧪 Interventions in This Study
- Hypercapnia treatment (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- John D. Dingell VA Medical Center, Detroit, MI — Detroit, Michigan
📞 Contact the Study Coordinator
Phone: (313) 576-1000
Email: Abdulghani.Sankari@va.gov
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Sleep Apnea
- Mechanisms of Prediabetic States in Sleep Apnea — Chicago, Illinois
- Technology-Supported Treatment of Sleep Apnea in Prediabetes — Chicago, Illinois
- Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep Apnea — La Jolla, California
- Behavioral Optimization to Overcome Obstructive Sleep Apnea Treatment Barriers — West Los Angeles, California
- Janus II Feasibility — Scottsdale, Arizona
- Sleep Disordered Breathing With Opioid Use — Detroit, Michigan
Explore by condition: All Sleep Apnea clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.