🏛️ Verified NIH Record • Updated 2026-07-12
A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough (NCT05600777)
A Phase 3, 24-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Arm Efficacy and Safety Study With Open-label Extension of BLU-5937 in Adult Participants With Refractory Chronic Cough Including Unexplained Chronic Cough (CALM-2)
🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Bellus Health Inc. - a GSK company
🩺 Plain-English Summary (8th-Grade Level)
This is a randomized, double-blind, placebo-controlled, parallel-arm, Phase 3 study of BLU-5937 in participants with Refractory Chronic Cough (RCC).
Who can join: Review the eligibility criteria below.
Location: GSK Investigational Site — Foley, Alabama
Age range: 18 Years to 80 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (242 Sites)
Showing the first 25 of 242 sites.
- GSK Investigational Site — Foley, Alabama
- GSK Investigational Site — Litchfield Park, Arizona
- GSK Investigational Site — Phoenix, Arizona
- GSK Investigational Site — Los Angeles, California
- GSK Investigational Site — Los Angeles, California
- GSK Investigational Site — Paramount, California
- GSK Investigational Site — Sacramento, California
- GSK Investigational Site — San Diego, California
- GSK Investigational Site — San Diego, California
- GSK Investigational Site — San Jose, California
- GSK Investigational Site — Aurora, Colorado
- GSK Investigational Site — Colorado Springs, Colorado
- GSK Investigational Site — Denver, Colorado
- GSK Investigational Site — Wheat Ridge, Colorado
- GSK Investigational Site — Washington D.C., District of Columbia
- GSK Investigational Site — Daytona Beach, Florida
- GSK Investigational Site — Fort Lauderdale, Florida
- GSK Investigational Site — Jacksonville, Florida
- GSK Investigational Site — Leesburg, Florida
- GSK Investigational Site — Orlando, Florida
- GSK Investigational Site — Santa Rosa Beach, Florida
- GSK Investigational Site — Sarasota, Florida
- GSK Investigational Site — Sweetwater, Florida
- GSK Investigational Site — Cumming, Georgia
- GSK Investigational Site — Chicago, Illinois
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cough
- A 2x2 Factorial, Randomized, Open-label Trial to Evaluate Neuromodulators and Cough Control Therapy in Patients With Refractory or Unexplained Chronic Cough — Calgary, Alberta
- Usefulness and Feasibility of Ultrasound in Office Laryngology Procedures — New York, New York
- Stimulation of the Larynx to Treat Unexplained Chronic Cough — Minneapolis, Minnesota
- A Non-pharmacological Cough Control Therapy — Hamilton, Ontario
- Office-Based Superior Laryngeal Nerve Block for Treatment of Neurogenic Cough — Birmingham, Alabama
Explore by condition: All Cough clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.