Physiological Effects of Continuous Negative External Pressure for Acute Hypoxemic Respiratory Failure (NCT05675345)
Physiological Effects of Continuous Negative External Pressure for Acute Hypoxemic Respiratory Failure: A Pilot Crossover Trial
🩺 Plain-English Summary (8th-Grade Level)
This study is being conducted to evaluate if wearing a non-invasive breathing support device over the chest/abdomen improves markers of breathing in patients with lung injury requiring high-flow oxygen. The breathing support device consists of a plastic shell that sits over the chest and abdomen and connects to a vacuum that helps the chest expand with breathing. This breathing support is known as continuous negative external pressure (CNEP). Study findings will help determine if this breathing support device might be useful for patients with acute hypoxemic respiratory failure (AHRF).
Who can join: Review the eligibility criteria below.
Location: Columbia University Irving Medical Center — New York, New York
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Columbia University Irving Medical Center — New York, New York
📞 Contact the Study Coordinator
Phone: (212) 305-0334
Email: jrb2266@cumc.columbia.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Acute Hypoxemic Respiratory Failure
- Assessment of PaO2/FiO2 Ratio Pre and POst INTubation — Chicago, Illinois
- HNFO With or Without Helmet NIV for Oxygenation Support in Acute Respiratory Failure Pilot RCT — Calgary, Alberta
- Adiposity Distribution in Acute Respiratory Failure — Boston, Massachusetts
- Protocolized Weaning of High-Flow Nasal Cannula in Adult Patients — Chicago, Illinois
- Pressure Muscle Index and Threshold of Over-assistance During Pressure Support Ventilation — Toronto, Ontario
Explore by condition: All Acute Hypoxemic Respiratory Failure clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.