πŸ›οΈ Verified NIH Record β€’ Updated 2026-05-13

Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (NCT05702229)

An Open-Label, Multi-Drug, Multi-Centre, Phase II Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

🟒 Recruiting Phase2 πŸ’Š Investigational Drug / Biologic Sponsor: AstraZeneca

🩺 Plain-English Summary (8th-Grade Level)

This is a Phase II, open-label, multi-drug, multi-centre study designed to assess the efficacy, safety, tolerability, pharmacokinetics, and immunogenicity of novel combination therapies in participants with locally advanced unresectable or metastatic gastric or GEJ adenocarcinoma.

Who can join: Review the eligibility criteria below.

Location: Research Site β€” Los Angeles, California

Age range: 18 Years

πŸ“‹ "Do I Qualify?" β€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria β†—

πŸ“ All Participating Trial Locations (44 Sites)

Showing the first 25 of 44 sites.

  • Research Site β€” Los Angeles, California
  • Research Site β€” Los Angeles, California
  • Research Site β€” Baton Rouge, Louisiana
  • Research Site β€” Grand Rapids, Michigan
  • Research Site β€” New Hyde Park, New York
  • Research Site β€” New York, New York
  • Research Site β€” New York, New York
  • Research Site β€” New York, New York
  • Research Site β€” Shirley, New York
  • Research Site β€” The Bronx, New York
  • Research Site β€” Pittsburgh, Pennsylvania
  • Research Site β€” Beijing,
  • Research Site β€” Hangzhou,
  • Research Site β€” Hangzhou,
  • Research Site β€” Harbin,
  • Research Site β€” Hefei,
  • Research Site β€” Kunming,
  • Research Site β€” Wuhan,
  • Research Site β€” Yinchuan,
  • Research Site β€” Zhengzhou,
  • Research Site β€” Chūōku,
  • Research Site β€” Kashiwa,
  • Research Site β€” Sunto-gun,
  • Research Site β€” Seoul,
  • Research Site β€” Seoul,

πŸ“ž Contact the Study Coordinator

Phone: (877) 240-9479

Email: information.center@astrazeneca.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

πŸ’° Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Gastric Cancer clinical trials

πŸ’‘ How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
πŸ›οΈ View Official NIH Record β†—