Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (NCT05702229)
An Open-Label, Multi-Drug, Multi-Centre, Phase II Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
π©Ί Plain-English Summary (8th-Grade Level)
This is a Phase II, open-label, multi-drug, multi-centre study designed to assess the efficacy, safety, tolerability, pharmacokinetics, and immunogenicity of novel combination therapies in participants with locally advanced unresectable or metastatic gastric or GEJ adenocarcinoma.
Who can join: Review the eligibility criteria below.
Location: Research Site β Los Angeles, California
Age range: 18 Years
π§ͺ Interventions in This Study
π "Do I Qualify?" β 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria β
π All Participating Trial Locations (44 Sites)
Showing the first 25 of 44 sites.
- Research Site β Los Angeles, California
- Research Site β Los Angeles, California
- Research Site β Baton Rouge, Louisiana
- Research Site β Grand Rapids, Michigan
- Research Site β New Hyde Park, New York
- Research Site β New York, New York
- Research Site β New York, New York
- Research Site β New York, New York
- Research Site β Shirley, New York
- Research Site β The Bronx, New York
- Research Site β Pittsburgh, Pennsylvania
- Research Site β Beijing,
- Research Site β Hangzhou,
- Research Site β Hangzhou,
- Research Site β Harbin,
- Research Site β Hefei,
- Research Site β Kunming,
- Research Site β Wuhan,
- Research Site β Yinchuan,
- Research Site β Zhengzhou,
- Research Site β ChΕ«Εku,
- Research Site β Kashiwa,
- Research Site β Sunto-gun,
- Research Site β Seoul,
- Research Site β Seoul,
π Contact the Study Coordinator
Phone: (877) 240-9479
Email: information.center@astrazeneca.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
π° Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03) β Baltimore, Maryland
- Nivolumab +/- Relatlimab Prior to Chemoradiation With II/III Gastro/Esophageal Cancer β Baltimore, Maryland
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π‘ How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.