๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-27

Open-Label Extension Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Plaque Psoriasis (NCT05739435)

A Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Patients With Plaque Psoriasis

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Alumis Inc

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a multi-center, open-label extension (OLE) study in patients with plaque psoriasis who have completed their participation in a previous plaque psoriasis study of ESK-001.

Who can join: Review the eligibility criteria below.

Location: Investigator Site # 1029 โ€” Birmingham, Alabama

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (38 Sites)

Showing the first 25 of 38 sites.

  • Investigator Site # 1029 โ€” Birmingham, Alabama
  • Investigator Site #1001 โ€” Phoenix, Arizona
  • Investigator Site # 1023 โ€” Rogers, Arkansas
  • Investigator Site #1021 โ€” Encinitas, California
  • Investigator Site #1018 โ€” Los Angeles, California
  • Investigator Site #1007 โ€” Santa Monica, California
  • Investigator Site #1002 โ€” Sherman Oaks, California
  • Investigator site # 1030 โ€” Fort Lauderdale, Florida
  • Investigator Site #1025 โ€” Hialeah, Florida
  • Investigator site # 1028 โ€” Miami, Florida
  • Investigator Site # 1013 โ€” Tampa, Florida
  • Investigator Site #1035 โ€” Macon, Georgia
  • Investigator Site #1043 โ€” Sandy Springs, Georgia
  • Investigator Site #1005 โ€” Rolling Meadows, Illinois
  • Investigator Site # 1011 โ€” Columbus, Indiana
  • Investigator Site #1027 โ€” South Bend, Indiana
  • Investigator SIte#1036 โ€” Overland Park, Kansas
  • Investigator Site #1017 โ€” Owensboro, Kentucky
  • Investigator Site #1026 โ€” Rockville, Maryland
  • Investigator Site #1010 โ€” Clarkston, Michigan
  • Investigator Site #1031 โ€” New Brighton, Minnesota
  • Investigator Site #1033 โ€” Norman, Oklahoma
  • Investigator Site #1019 โ€” Portland, Oregon
  • Investigator Site #1022 โ€” Philadelphia, Pennsylvania
  • Investigator Site # 1012 โ€” Rapid City, South Dakota

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Plaque Psoriasis clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—