๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-05-29

A Study of TAK-279 in Participants With Moderate-to-Severe Plaque Psoriasis (NCT06550076)

A Phase 3, Multicenter, Open-Label Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of TAK-279 in Subjects With Moderate-to-Severe Plaque Psoriasis

๐Ÿ”ต Active, Not Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Takeda

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The main aim of this study is to check the side effects of TAK-279 and how well it is tolerated in participants with moderate-to-severe plaque psoriasis. All participants will be assigned to study treatments of TAK-279 and will be treated with TAK-279 if the participants meet the study rules. Participants will be in the study for up to 217 weeks, including up to 35 days for the screening period, 52 weeks (Part A) up to 156 additional weeks (Part B) study treatment and 4 weeks follow up period. During the study, participants will visit their study clinic multiple times.

Who can join: Review the eligibility criteria below.

Location: Total Dermatology โ€” Birmingham, Alabama

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (278 Sites)

Showing the first 25 of 278 sites.

  • Total Dermatology โ€” Birmingham, Alabama
  • University of Alabama Hospital - Whitaker Clinic - โ€” Birmingham, Alabama
  • Cahaba Dermatology Skin Health Center โ€” Hoover, Alabama
  • Medical Dermatology Specialists โ€” Phoenix, Arizona
  • Saguaro Dermatology Associates, LLC - Probity - PPDS โ€” Phoenix, Arizona
  • Noble Clinical Research โ€” Tucson, Arizona
  • Johnson Dermatology Clinic โ€” Fort Smith, Arkansas
  • Burke Pharmaceutical Research โ€” Hot Springs, Arkansas
  • Zenith Research, Inc. โ€” Beverly Hills, California
  • First OC Dermatology Research Inc. โ€” Fountain Valley, California
  • Center for Dermatology Clinical Research โ€” Fremont, California
  • Long Beach Research Institute โ€” Long Beach, California
  • Metropolis Dermatology Downtown LA - Probity - PPDS โ€” Los Angeles, California
  • UCLA University of California Los Angeles โ€” Los Angeles, California
  • Northridge Clinical Trials โ€” Northridge, California
  • UC Davis Dermatology Clinic โ€” Sacramento, California
  • TCR Medical Corporation โ€” San Diego, California
  • University Clinical Trials โ€” San Diego, California
  • Dermatology Institute and Skin Care Center โ€” Santa Monica, California
  • UNISON Clinical Trials (Shahram Jacobs md inc.) โ€” Sherman Oaks, California
  • Driven Research LLC โ€” Coral Gables, Florida
  • Revival Research Corporation - Florida - ClinEdge - PPDS โ€” Doral, Florida
  • FXM Clinical Research Ft. Lauderdale, LLC โ€” Fort Lauderdale, Florida
  • Direct Helpers Medical Center โ€” Hialeah, Florida
  • Florida Academic Centers Research โ€” Miami, Florida

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Plaque Psoriasis clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—