🏛️ Verified NIH Record • Updated 2025-11-18
A Study of Ado-trastuzumab Emtansine (T-DM1)-Induced Peripheral Neuropathy in HER2-positive Breast Cancer Patients (NCT05889988)
A Study of the Natural History of Ado-trastuzumab Emtansine (T-DM1)-Induced Peripheral Neuropathy in HER2-positive Breast Cancer Patients
🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Mayo Clinic
🩺 Plain-English Summary (8th-Grade Level)
Researchers plan to study the natural history of ado-trastuzumab emtansine (T-DM1)-induced neuropathy both in patients without any history of neuropathy or previous neurotoxic agent use and in patients who have such a history.
Who can join: Review the eligibility criteria below.
Location: Riverwood Healthcare Center — Aitkin, Minnesota
Age range: 18 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (21 Sites)
- Riverwood Healthcare Center — Aitkin, Minnesota
- Essentia Health Baxter Clinic — Baxter, Minnesota
- Essentia Health Saint Joseph's Medical Center — Brainerd, Minnesota
- Essentia Health - Deer River Clinic — Deer River, Minnesota
- Essentia Health Saint Mary's - Detroit Lakes Clinic — Detroit Lakes, Minnesota
- Essentia Health Cancer Center — Duluth, Minnesota
- Essentia Health Ely Clinic — Ely, Minnesota
- Essentia Health - Fosston — Fosston, Minnesota
- Fairview Grand Itasca Clinic & Hospital — Grand Rapids, Minnesota
- Essentia Health Hibbing Clinic — Hibbing, Minnesota
- Fairview Range Medical Center — Hibbing, Minnesota
- Essentia Health - International Falls Clinic — International Falls, Minnesota
- MMCORC CentraCare Monticello Cancer Center — Monticello, Minnesota
- Essentia Health Moose Lake — Moose Lake, Minnesota
- Essentia Health - Park Rapids — Park Rapids, Minnesota
- Fairview Northland Medical Center — Princeton, Minnesota
- Mayo Clinic in Rochester — Rochester, Minnesota
- Essentia Health Sandstone — Sandstone, Minnesota
- Sanford Health Thief River Falls Clinic — Thief River Falls, Minnesota
- Essentia Health Virginia Clinic — Virginia, Minnesota
- Sanford Health Worthington — Worthington, Minnesota
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.