Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging (NCT05907629)
🩺 Plain-English Summary (8th-Grade Level)
CAPTIVA-MRI is an observational multimodal MR imaging study that is ancillary to the CAPTIVA trial \[a 3-arm, double-blind Phase III trial conducted at approximately 115 StrokeNet sites randomizing patients with stroke attributed to 70-99% intracranial atherosclerotic stenosis (ICAS) to aspirin plus ticagrelor, clopidogrel, or rivaroxaban.\] The primary goal of this ancillary study is to determine if MRI biomarkers can potentially identify ICAS patients who fail best medical management. The CAPTIVA-MRI study leverages the CAPTIVA trial design and implementation to capture information that will inform and facilitate the next generation of ICAS trials and the management of patients with ICAS.
Who can join: Review the eligibility criteria below.
Location: University of Alabama Hospital — Birmingham, Alabama
Age range: 18 Years
🧪 Interventions in This Study
- MRI (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (28 Sites)
Showing the first 25 of 28 sites.
- University of Alabama Hospital — Birmingham, Alabama
- University of Colorado Hospital — Aurora, Colorado
- Hartford Hospital — Hartford, Connecticut
- Yale New Haven Hospital — New Haven, Connecticut
- MedStar Washington Hospital Center — Washington D.C., District of Columbia
- Baptist Medical Center Jacksonville — Jacksonville, Florida
- Jackson Memorial Hospital, Miami — Miami, Florida
- Cleveland Clinic Tradition Hospital — Port Saint Lucie, Florida
- SIH Memorial Hospital of Carbondale — Carbondale, Illinois
- University of Illinois Hospital — Chicago, Illinois
- University of Chicago Medical Center — Chicago, Illinois
- Metro Health Hospital — Wyoming, Michigan
- M Health Fairview University of Minnesota Medical Center — Minneapolis, Minnesota
- Barnes Jewish Hospital — St Louis, Missouri
- Buffalo General Medical Center — Buffalo, New York
- North Shore University Hospita — Manhasset, New York
- NYP Columbia University Medical Center — New York, New York
- Carolinas Medical Center — Charlotte, North Carolina
- Duke University Hospital — Durham, North Carolina
- Cleveland Clinic Akron General — Akron, Ohio
- University of Cincinnati Medical Center — Cincinnati, Ohio
- UH Cleveland Medical Center — Cleveland, Ohio
- Mercy St. Vincent Medical Center — Toledo, Ohio
- Prisma Health Richland Hospital — Columbia, South Carolina
- University of Texas Medical Branch — Galveston, Texas
📞 Contact the Study Coordinator
Phone: (801) 585-7575
Email: ka-ho.wong@hsc.utah.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.