๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-20

Prospective, Multi-Center, Observational, Whole Blood Specimen Collection Study in Participants With Rheumatoid Arthritis With Inadequate Response or Intolerance to a DMARD Starting a New bDMARD or tsDMARD Treatment +/- csDMARD (NCT05936970)

๐Ÿ”ต Active, Not Recruiting Interventional Protocol ๐Ÿ“Š Observational Clinical Research Sponsor: Aqtual, Inc.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The primary goal of this study is to assess a cfDNA-based blood test using genetic, transcriptomic and/or epigenetic information to help doctors predict the best treatment options for rheumatoid arthritis (RA) patients with inadequate response or intolerance to previous therapies.

Who can join: Review the eligibility criteria below.

Location: Arizona Arthritis & Rheumatology Research โ€” Phoenix, Arizona

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (42 Sites)

Showing the first 25 of 42 sites.

  • Arizona Arthritis & Rheumatology Research โ€” Phoenix, Arizona
  • Medvin Clinical Research - Apple Valley โ€” Apple Valley, California
  • Medvin Clinical Research - Covina โ€” Covina, California
  • Medvin Clinical Research - Riverside โ€” Riverside, California
  • Medvin Clinical Research - Tujunga โ€” Tujunga, California
  • Medvin Clinical Research - Whittier โ€” Whittier, California
  • AARDS Research, Inc โ€” Aventura, Florida
  • Highlands Advanced Rheumatology and Arthritis Center (HARAC) โ€” Avon Park, Florida
  • Bay Area Rheumatology โ€” Clearwater, Florida
  • Believe Clinical Trials โ€” Coral Springs, Florida
  • GNP Research โ€” Hollywood, Florida
  • Life Clinical Trials โ€” Margate, Florida
  • Vitalia Medical Research โ€” Palm Beach Gardens, Florida
  • Shine a Light Research โ€” Sun City Center, Florida
  • West Broward Rheumatology Associates โ€” Tamarac, Florida
  • St. Luke's Clinic โ€” Boise, Idaho
  • Arnold Arthritis & Rheumatology โ€” Skokie, Illinois
  • Illinois Bone and Joint Institute โ€” Willowbrook, Illinois
  • Lake Cumberland Rheumatology โ€” New Albany, Indiana
  • Clinical Research Institute of Michigan โ€” Saint Clair Shores, Michigan
  • St. Paul Rheumatology โ€” Eagan, Minnesota
  • AARA/Kansas City Physician Partners โ€” Kansas City, Missouri
  • New England Rheumatology & Osteoporosis โ€” Henniker, New Hampshire
  • Arthritis Rheumatism and Bone Disease Associates โ€” Voorhees Township, New Jersey
  • Sahni Rheumatology & Therapy โ€” West Long Branch, New Jersey

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—