Long COVID Immune Profiling (NCT06027255)
๐ฉบ Plain-English Summary (8th-Grade Level)
Parasympathetic nervous system (PNS) is part of the body's autonomic nervous system(PNS) protects body against inflammation. Study shows that reduced PNS function activity is associated with persistent inflammation. Preliminary data from the studies shows, that post-COVID-19 POTS patients have reduced parasympathetic (PNS) function. Given that the PNS protects against inflammation, this clinical trial aims to prove that post-COVID-19 POTS is caused by reduced PNS activity, which in turn, contributes to persistent inflammation, orthostatic intolerance, and OI symptoms. The study will evaluate immune cell activation in post-COVID-19 POTS and patients with history of COVID-19 infection without sequelae and correlate this with the degree of decreased PNS activity.
Who can join: Review the eligibility criteria below.
Location: Cyndya Shibao โ Nashville, Tennessee
Age range: 18 Years
๐งช Interventions in This Study
- IL-6 (DIAGNOSTIC_TEST)
- cytokines (IL-17, and IFN-ษฃ) (DIAGNOSTIC_TEST)
- Compass 31 (BEHAVIORAL)
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (1 Sites)
- Cyndya Shibao โ Nashville, Tennessee
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Long COVID
- Ensitrelvir for Viral Persistence and Inflammation in People Experiencing Long COVID โ San Francisco, California
- The Long COVID Treatment Trial โ La Jolla, California
- tVNS in Long COVID-19 โ New York, New York
- Nutritional Management of Post COVID-19 Cognitive Symptoms โ Edmonton, Alberta
- Pain in Long COVID-19: the Role of Sleep โ Boston, Massachusetts
Explore by condition: All Long COVID clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.