Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples (NCT06071845)
Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples for the Non-endoscopic Detection of Barrett's Esophagus With and Without Dysplasia
🩺 Plain-English Summary (8th-Grade Level)
This clinical trial evaluates the use of cytosponge, a minimally invasive collection device, for the detection of Barrett's esophagus (BE) in patients undergoing endoscopy. Non-endoscopic swallowable encapsulate sponge cell collection devices combined with markers for BE/esophageal adenocarcinoma (EAC) detection are a guideline-endorsed alternative to endoscopy for BE screening. The Oncoguard registered trademark Esophagus test (OGE) test uses esophageal cytology specimens collected with a minimally invasive, non-endoscopic, encapsulated sponge sampling device to identify BE/EAC biomarkers that indicate whether a patient should undergo diagnostic endoscopy. The OGE test is a simple and cost effective screening method that may lower barriers to widespread adoption of BE screening in at risk patients, resulting in increased and earlier detection of BE/EAC.
Who can join: Review the eligibility criteria below.
Location: Mayo Clinic — Scottsdale, Arizona
Age range: 18 Years to 90 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (5 Sites)
- Mayo Clinic — Scottsdale, Arizona
- Mayo Clinic in Florida — Jacksonville, Florida
- Northwestern University — Chicago, Illinois
- Mayo Clinic in Rochester — Rochester, Minnesota
- Long Island Jewish Medical Center | Northwell Health — New Hyde Park, New York
📞 Contact the Study Coordinator
Phone: (855) 776-0015
Email: mayocliniccancerstudies@mayo.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Barrett Esophagus
- Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus — Baltimore, Maryland
- Coordinating Center: Natural History of Barrett's Esophagus Using Tethered Capsule Endomicroscopy — Jacksonville, Florida
- Nitrous Oxide For Endoscopic Ablation of Refractory Barrett's Esophagus (NO FEAR-BE) — Birmingham, Alabama
- Natural History of Barrett's Esophagus Using Tethered Capsule Endomicroscopy — Boston, Massachusetts
- Multi-center Clinical Study to Evaluate the C2 CryoBalloon Focal Ablation System — Orange, California
- Aspirin in Preventing Disease Recurrence in Patients With Barrett Esophagus After Successful Elimination by Radiofrequency Ablation — Los Angeles, California
Explore by condition: All Barrett Esophagus clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.