A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation (NCT06179160)
A Phase 1, Open-Label, Multicenter Study of INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
๐ฉบ Plain-English Summary (8th-Grade Level)
This study is conducted to determine the safety and tolerability of INCB161734 as a single agent or in combination with other anticancer therapies.
Who can join: Review the eligibility criteria below.
Location: Mayo Clinic Hospital โ Phoenix, Arizona
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (34 Sites)
Showing the first 25 of 34 sites.
- Mayo Clinic Hospital โ Phoenix, Arizona
- Stanford University โ Palo Alto, California
- UCLA Healthcare Hematology-Oncology โ Santa Monica, California
- Sarah Cannon Research Institue At Healthone โ Denver, Colorado
- Florida Cancer Specialists โ Sarasota, Florida
- Sidney Kimmel Comprehensive Cancer Center At Johns Hopkins โ Baltimore, Maryland
- Dana Farber Cancer Institute โ Boston, Massachusetts
- Hackensack University Medical Center โ Hackensack, New Jersey
- Weill Cornell Medicine โ New York, New York
- Memorial Sloan Kettering Cancer Center โ New York, New York
- Jefferson University Hospitals โ Philadelphia, Pennsylvania
- Scri Oncology Partners โ Nashville, Tennessee
- Md Anderson Cancer Center โ Houston, Texas
- Chris Obrien Lifehouse โ Camperdown, New South Wales
- St Vincent'S Hospital Sydney โ Darlinghurst, New South Wales
- Peter Maccallum Cancer Centre โ Melbourne, Victoria
- The Alfred Hospital โ Melbourne, Victoria
- Linear Clinical Research โ Nedlands, Western Australia
- Cliniques Universitaires Ucl Saint-Luc โ Brussels,
- Universitair Ziekenhuis Antwerpen (Uza) โ Edegem,
- Universitair Ziekenhuis (Uz) Leuven โ Leuven,
- The Ottawa Hospital Cancer Center โ Ottawa, Ontario
- Princess Margaret Cancer Center โ Toronto, Ontario
- Centre Leon Berard โ Lyon,
- Universitaire Du Cancer de Toulouse Institut Claudius Regaud Iuct-Oncopole โ Toulouse,
๐ Contact the Study Coordinator
Phone: (855) 463-3463
Email: medinfo@incyte.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Solid Tumors
- Study of Pembrolizumab Following Surgery in Patients With Microsatellite Instability High (MSI-H) Solid Tumors โ Basking Ridge, New Jersey
- Study of the Effect of Rifampicin on the Pharmacokinetics (PK) of Multiple Doses of Cediranib in Patients With Solid Tumours โ Edmonton, Alberta
- Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor) โ Santa Monica, California
- A Safety and Efficacy Extension Study of Pertuzumab in Patients With Solid Tumors Previously Enrolled in a Hoffmann-La Roche-Sponsored Pertuzumab Clinical Trial โ Porto Alegre, Rio Grande do Sul
- Safety, Tolerability, and Immunogenicity of mRNA-4157 Alone and in Combination in Participants With Solid Tumors โ Los Angeles, California
- Flavored, Oral Irinotecan VAL-413 (Orotecanยฎ) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors โ Phoenix, Arizona
Explore by condition: All Solid Tumors clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.