๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-20

A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation (NCT06179160)

A Phase 1, Open-Label, Multicenter Study of INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

๐ŸŸข Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Incyte Corporation

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This study is conducted to determine the safety and tolerability of INCB161734 as a single agent or in combination with other anticancer therapies.

Who can join: Review the eligibility criteria below.

Location: Mayo Clinic Hospital โ€” Phoenix, Arizona

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (34 Sites)

Showing the first 25 of 34 sites.

  • Mayo Clinic Hospital โ€” Phoenix, Arizona
  • Stanford University โ€” Palo Alto, California
  • UCLA Healthcare Hematology-Oncology โ€” Santa Monica, California
  • Sarah Cannon Research Institue At Healthone โ€” Denver, Colorado
  • Florida Cancer Specialists โ€” Sarasota, Florida
  • Sidney Kimmel Comprehensive Cancer Center At Johns Hopkins โ€” Baltimore, Maryland
  • Dana Farber Cancer Institute โ€” Boston, Massachusetts
  • Hackensack University Medical Center โ€” Hackensack, New Jersey
  • Weill Cornell Medicine โ€” New York, New York
  • Memorial Sloan Kettering Cancer Center โ€” New York, New York
  • Jefferson University Hospitals โ€” Philadelphia, Pennsylvania
  • Scri Oncology Partners โ€” Nashville, Tennessee
  • Md Anderson Cancer Center โ€” Houston, Texas
  • Chris Obrien Lifehouse โ€” Camperdown, New South Wales
  • St Vincent'S Hospital Sydney โ€” Darlinghurst, New South Wales
  • Peter Maccallum Cancer Centre โ€” Melbourne, Victoria
  • The Alfred Hospital โ€” Melbourne, Victoria
  • Linear Clinical Research โ€” Nedlands, Western Australia
  • Cliniques Universitaires Ucl Saint-Luc โ€” Brussels,
  • Universitair Ziekenhuis Antwerpen (Uza) โ€” Edegem,
  • Universitair Ziekenhuis (Uz) Leuven โ€” Leuven,
  • The Ottawa Hospital Cancer Center โ€” Ottawa, Ontario
  • Princess Margaret Cancer Center โ€” Toronto, Ontario
  • Centre Leon Berard โ€” Lyon,
  • Universitaire Du Cancer de Toulouse Institut Claudius Regaud Iuct-Oncopole โ€” Toulouse,

๐Ÿ“ž Contact the Study Coordinator

Phone: (855) 463-3463

Email: medinfo@incyte.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Solid Tumors clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—