🏛️ Verified NIH Record • Updated 2026-07-28

AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2 (NCT06219941)

A Phase II, Open-label, Multi-centre Study to Evaluate Safety, Tolerability, Efficacy, PK, and Immunogenicity of AZD0901 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Tumours Expressing Claudin 18.2 (CLARITY-PanTumour01)

🟢 Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: AstraZeneca

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to assess the safety, tolerability, efficacy, pharmacokinetics (PK), and immunogenicity of AZD0901 as monotherapy and in combination with anti-cancer agents in participants with locally advanced unresectable or metastatic solid tumours expressing CLDN18.2.

Who can join: Review the eligibility criteria below.

Location: Research Site — Orange, California

Age range: 18 Years

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (52 Sites)

Showing the first 25 of 52 sites.

  • Research Site — Orange, California
  • Research Site — Palo Alto, California
  • Research Site — Santa Rosa, California
  • Research Site — Louisville, Kentucky
  • Research Site — Commack, New York
  • Research Site — Providence, Rhode Island
  • Research Site — Houston, Texas
  • Research Site — Melbourne,
  • Research Site — Murdoch,
  • Research Site — Randwick,
  • Research Site — Kingston, Ontario
  • Research Site — Toronto, Ontario
  • Research Site — Montreal, Quebec
  • Research Site — Sherbrooke, Quebec
  • Research Site — Changsha,
  • Research Site — Chengdu,
  • Research Site — Tbilisi,
  • Research Site — Chūōku,
  • Research Site — Kashiwa,
  • Research Site — Kitaadachi-gun,
  • Research Site — Kōtoku,
  • Research Site — Nagoya,
  • Research Site — Osakasayama-shi,
  • Research Site — George Town,
  • Research Site — Johor Bahru,

📞 Contact the Study Coordinator

Phone: (877) 240-9479

Email: information.center@astrazeneca.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗