๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-20

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease (NCT06226883)

A Phase 2, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of 3 Active Dose Regimens of MORF-057 in Adults With Moderately to Severely Active Crohn's Disease (GARNET)

๐ŸŸข Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a Phase 2, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of 3 active dose regimens of MORF-057 in adult study participants with moderately to severely active Crohn's disease (CD).

Who can join: Review the eligibility criteria below.

Location: Gastro Care Institute โ€” Lancaster, California

Age range: 18 Years to 85 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (225 Sites)

Showing the first 25 of 225 sites.

  • Gastro Care Institute โ€” Lancaster, California
  • Infinity Clinical Research โ€” San Diego, California
  • Peak Gastroenterology Associates - Colorado Springs โ€” Colorado Springs, Colorado
  • Clinical Research of Osceola โ€” Kissimmee, Florida
  • Bioresearch Partner-Kendale Lakes โ€” Miami, Florida
  • Endoscopic Research Inc โ€” Orlando, Florida
  • Tropical Clinical Trials โ€” Palmetto Bay, Florida
  • Atlanta Gastroenterology Specialists, PC โ€” Atlanta, Georgia
  • Atlanta Gastroenterology Associates (Part of United Digestive) โ€” Atlanta, Georgia
  • Tandem Clinical Research โ€” Houma, Louisiana
  • SSM Health DePaul Hospital- St. Louis โ€” Bridgeton, Missouri
  • Las Vegas Clinical Trials โ€” North Las Vegas, Nevada
  • Cross Creek Medical Clinic โ€” Fayetteville, North Carolina
  • Peters Medical Research โ€” High Point, North Carolina
  • Wake Research Associates โ€” Raleigh, North Carolina
  • Palmetto Gastroenterology Clinical Research โ€” Summerville, South Carolina
  • Gastrointestinal Associates of Northeast Tennessee โ€” Johnson City, Tennessee
  • GI Alliance - Cedar Park โ€” Cedar Park, Texas
  • North Texas Gastroenterology โ€” Denton, Texas
  • The University of Texas Health Science Center at Houston โ€” Houston, Texas
  • Prime Clinical Research - Lewisville โ€” Lewisville, Texas
  • Prime Clinical Research โ€” Mansfield, Texas
  • Tyler Research Institute, LLC โ€” Tyler, Texas
  • Care Access Research - Ogden โ€” Ogden, Utah
  • Gastroenterology Associates of Central Virginia โ€” Lynchburg, Virginia

๐Ÿ“ž Contact the Study Coordinator

Phone: (317) 615-4559

Email: LillyTrials@Lilly.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—