Reducing Gastrointestinal Bleeding With Proton Pump Inhibitor Therapy in Acute Venous Thromboembolism (NCT06393868)
Reducing Gastrointestinal Bleeding With Proton Pump Inhibitor Therapy in Acute Venous Thromboembolism: Pilot Randomized Study (RADIANT Study)
🩺 Plain-English Summary (8th-Grade Level)
The investigators are studying whether treatment with a proton pump inhibitor called omeprazole reduces gastrointestinal bleeding in older adults taking blood thinners for a blood clot (venous thromboembolism). The purpose of this study, a pilot study or a feasibility study, is to test the study plan and determine whether enough participants will join a larger study and accept the study procedures.
Who can join: Review the eligibility criteria below.
Location: The Ottawa Hospital — Ottawa, Ontario
Age range: 65 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (7 Sites)
- The Ottawa Hospital — Ottawa, Ontario
- Niagara Health System - St. Catharines Site — St. Catharines, Ontario
- University Health Network - Toronto General — Toronto, Ontario
- CIUSSS de l'Est-de- l'Île-de-Montréal — Montreal, Quebec
- Centre hospitalier de l'Université de Montréal — Montreal, Quebec
- CHU de Québec-Université Laval; Hôpital Saint-François d'Assise — Québec, Quebec
- Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval — Québec, Quebec
📞 Contact the Study Coordinator
Phone: (613) 737-8899
Email: dsiegal@toh.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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Explore by condition: All Venous Thromboembolism clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.