πŸ›οΈ Verified NIH Record β€’ Updated 2026-04-23

Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis (NCT06408259)

A Phase 3, Multicenter, Double-blind, Active-controlled Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Oral Ozanimod Compared to Oral Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis

🟒 Recruiting Phase3 πŸ’Š Investigational Drug / Biologic Sponsor: Bristol-Myers Squibb

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to evaluate the effectiveness, safety, tolerability, drug levels and drug effects of ozanimod compared to fingolimod in children and adolescents with relapsing remitting multiple sclerosis (RRMS).

Who can join: Review the eligibility criteria below.

Location: Local Institution - 0114 β€” Loma Linda, California

Age range: 10 Years to 17 Years

πŸ§ͺ Interventions in This Study

πŸ“‹ "Do I Qualify?" β€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria β†—

πŸ“ All Participating Trial Locations (33 Sites)

Showing the first 25 of 33 sites.

  • Local Institution - 0114 β€” Loma Linda, California
  • University of California Davis Health β€” Sacramento, California
  • University of South Florida β€” Tampa, Florida
  • Local Institution - 0093 β€” Chicago, Illinois
  • University of Chicago Medical Center β€” Chicago, Illinois
  • University of Louisville, Norton Children's Research Institute β€” Louisville, Kentucky
  • Local Institution - 0131 β€” New Brunswick, New Jersey
  • Local Institution - 0132 β€” Teaneck, New Jersey
  • Local Institution - 0091 β€” Cincinnati, Ohio
  • Local Institution - 0092 β€” Portland, Oregon
  • Local Institution - 0133 β€” El Paso, Texas
  • Medical College of Wisconsin β€” Milwaukee, Wisconsin
  • Royal Children's Hospital β€” Melbourne, Victoria
  • University of Naples Federico II β€” Naples, Campania
  • Ospedale San Raffaele β€” Milan, Lombardy
  • Local Institution - 0081 β€” Milan, Lombardy
  • Neurological Center Of Latium β€” Rome, Roma
  • Local Institution - 0078 β€” Mexico City, DIF
  • Uniwersytecki Szpital Kliniczny w Poznaniu β€” Poznan, Greater Poland Voivodeship
  • 2Ca Braga β€” Braga,
  • Unidade Local de SaΓΊde de Coimbra, E.P.E. β€” Coimbra,
  • Centro Hospitalar de Lisboa Central β€” Lisbon,
  • Local Institution - 0102 β€” Porto,
  • Local Institution - 0134 β€” Caguas,
  • Spitalul Clinic de Copii Doctor Victor Gomoiu β€” Bucharest, Bucharest

πŸ“ž Contact the Study Coordinator

Phone: (855) 907-3286

Email: Clinical.Trials@bms.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

πŸ’° Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

πŸ’‘ How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
πŸ›οΈ View Official NIH Record β†—