fMRI in CardiaC arrEst With Uncertain Prognosis (NCT06423768)
The fMRI in CardiaC arrEst With Uncertain Prognosis (FACE-UP) Study
🩺 Plain-English Summary (8th-Grade Level)
The goal of this observational study is to determine whether specific advanced MRI measures are associated with functional outcomes in patients who are comatose after cardiac arrest. The main question\[s\] it aims to answer are: Aim 1: Determine if stimulus-based functional MRI (fMRI)-measured activations are independently associated with favorable neurological outcomes after cardiac arrest Aim 2: Determine if resting state functional MRI (rs-fMRI)-measured functional network connectivity is independently associated with favorable neurological outcomes after cardiac arrest. Aim 3: Determine if diffusion tensor imaging (DTI)-measured white matter integrity is associated with favorable neurological outcomes after cardiac arrest. Participants will undergo advanced MRI sequences at time of clinical MRI, and will be followed for 6 months post-arrest.
Who can join: Review the eligibility criteria below.
Location: Brigham and Women's Hospital — Boston, Massachusetts
Age range: 18 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (2 Sites)
- Brigham and Women's Hospital — Boston, Massachusetts
- Brigham and Women's Hospital — Brookline, Massachusetts
📞 Contact the Study Coordinator
Phone: (857) 307-2391
Email: ssnider@bwh.harvard.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cardiac Arrest
- RACE-CARS - RAndomized Cluster Evaluation of Cardiac ARrest Systems — Durham, North Carolina
- Sustained Inflation and Chest Compression vs 3:1 C:V Ratio in Asphyxiated Newborns — Edmonton,
- Optimizing Ventilation to Improve Survival From Out-of-hospital Cardiac Arrest: the OPTIVO Randomized Controlled Trial — Toronto, Ontario
- Targeted Temperature Management at 33°C Versus Controlled Normothermia for In-hospital Cardiac Arrest — Brussels,
- Impact of Aerosol Box Use During Cardiopulmonary Arrest: A Multicenter Study — Los Angeles, California
- Early Amiodarone in Shockable Cardiac Arrest — Portland, Oregon
Explore by condition: All Cardiac Arrest clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.