🏛️ Verified NIH Record • Updated 2026-05-20

International Care Bundle Evaluation in Cerebral Hemorrhage Research (NCT06429332)

International Care Bundle Evaluation in Cerebral Hemorrhage Research - a Batched Parallel Cluster-randomized Trial With a Baseline Period

🟢 Recruiting Phase4 📋 Clinical Research Protocol Sponsor: Region Skane

🩺 Plain-English Summary (8th-Grade Level)

Spontaneous intracerebral haemorrhage (ICH) accounts for approximately 10-15% of all strokes but stands for 50% of stroke-related morbidity and mortality. Approximately half of all patients with ICH have a decreased level of consciousness at hospital admission. Despite this, intensive care and neurosurgical interventions are uncommon. A study conducted in low- and middle-income countries has demonstrated a beneficial effect of a treatment package consisting of early intensive blood pressure lowering, as well as the treatment of pyrexia and elevated blood glucose levels. The I-CATCHER team is now planning to conduct a similar study in Sweden and Australia, as well as in other high-income countries. The study has a clear focus on implementation, aiming to improve treatment and prognosis for patients with ICH within a few years. The purpose of I-CATCHER is to investigate whether a structured treatment package (Care Bundle) improves 3-month prognosis in patients with spontaneous ICH compared to standard care.

Who can join: Review the eligibility criteria below.

Location: The University of Oklahoma Health — Oklahoma City, Oklahoma

Age range: 18 Years

🧪 Interventions in This Study

  • Reversal of Oral anticoagulation within 30 minutes (OTHER)
  • Early intensive blood pressure lowering (OTHER)
  • Treatment of pyrexia (OTHER)
  • Hyperglycemia treatment (OTHER)
  • Do-not-resuscitate (DNR) or withdrawal of care (OTHER)
  • Referral to Intensive Care (OTHER)
  • Referral to Neurosurgery (OTHER)
  • Repeat brain imaging (DIAGNOSTIC_TEST)
  • Standard care (OTHER)

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (54 Sites)

Showing the first 25 of 54 sites.

  • The University of Oklahoma Health — Oklahoma City, Oklahoma
  • Royal Adelaide Hospital — Adelaide,
  • Monash Medical Centre — Clayton,
  • The George Institute for Global Health — Sydney,
  • Health Sciences North/Health Sciences North Research Institute — Greater Sudbury, Ontario
  • Hamilton General Hospital — Hamilton, Ontario
  • Ottawa Hospital Research Institute — Ottawa, Ontario
  • Hong Kong University Hospital — Hong Kong,
  • Landspitali University Hospital — Reykjavik,
  • Avezzano Ospedale SS. Filippo e Nicola — Avezzano,
  • Citta di Castello Ospedale Città di Castello — Città di Castello,
  • Gubbio Ospedale di Gubbio e Gualdo Tadino — Gubbio,
  • Azienda Ospedaliera Santa Maria della Misericordia Perugia — Perugia,
  • Roma Policlinico Gemelli — Roma,
  • National University of Malaysia Hospital — Kuala Lumpur,
  • Universiti Putra Malaysia Hospital — Serdang,
  • Höglandssjukhuset i Eksjö — Eksjö,
  • Sahlgrenska Universitetssjukhuset — Gothenburg,
  • Östra Sjukhuset — Gothenburg,
  • Hässleholms Sjukhus — Hässleholm,
  • Helsingborgs Lasarett — Helsingborg,
  • Karolinska Universitetssjukhuset Huddinge — Huddinge,
  • Länssjukhuset Ryhov — Jönköping,
  • Länssjukhuset Kalmar — Kalmar,
  • Blekingesjukhuset Karlskrona — Karlskrona,

📞 Contact the Study Coordinator

Phone: (004) 617-5057

Email: i-catcher@med.lu.se

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗