Neuroplasticity Biomarkers in Aphasia (NCT06471127)
Genetic and MRI Biomarkers of Neuroplasticity Predict Aphasia Recovery and Phenotypes
🩺 Plain-English Summary (8th-Grade Level)
Patients with stroke frequently suffer from aphasia, a disorder of expressive and/or receptive language, that can lead to serious health consequences, including social isolation, depression, reduced quality of life, and increased caregiver burden. Aphasia recovery varies greatly between individuals, and likely relies upon the capacity for neuroplasticity, both at a systems level of reorganized brain networks and a molecular level of neuronal repair and plasticity. The proposed work will evaluate genetic and neural network biological markers of neuroplasticity associated with variability in aphasia, with a future goal to improve prognostics and identify therapeutic targets to reduce the long-term burdens of aphasia.
Who can join: Review the eligibility criteria below.
Location: UW School of Medicine and Public Health — Madison, Wisconsin
Age range: 40 Years to 90 Years
🧪 Interventions in This Study
- Pseudoword learning paradigm task (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- UW School of Medicine and Public Health — Madison, Wisconsin
📞 Contact the Study Coordinator
Phone: (608) 890-0628
Email: hdresang@wisc.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Aphasia
- Semantic Feature Analysis Treatment for Aphasia — Pittsburgh, Pennsylvania
- Genetic and Cognitive Predictors of Aphasia Treatment Response — Columbus, Ohio
- Treatment Outcomes With tDCS in Post-Stroke Aphasia — Little Rock, Arkansas
- Brain-based Understanding of Individual Language Differences After Stroke — Washington D.C., District of Columbia
- HD-tDCS for Phonological Impairment in Aphasia — Milwaukee, Wisconsin
- Effects of Semantic Context on Criterion-learning Naming Treatment in Aphasia — Elkins Park, Pennsylvania
Explore by condition: All Aphasia clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.