Who is eligible for clinical trial NCT06473779?

Participants must meet protocol criteria for Severe Asthma. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT06473779 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-06-12

Open-label Study to Assess Reduction of Background Asthma Medication While Sustaining Asthma Control and Clinical Remission With Tezepelumab in Patients 12-80yrs With Severe Asthma. (NCT06473779)

A Multicentre, Randomised, Open-Label, Parallel-Group, Phase IIIb Study to Assess the Potential for Tezepelumab-treated Patients With Severe Asthma to Reduce Background Therapy While Sustaining Asthma Control and Clinical Remission

🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: AstraZeneca

🩺 Plain-English Summary (8th-Grade Level)

The objective of this study is to assess the potential for tezepelumab-treated patients (subcutaneous administration) to reduce maintenance therapy without loss of asthma control in adolescent and adults with severe asthma.. Study details include: 1. The study duration will be up to 72 weeks. 2. The treatment duration will be up to 68 weeks. 3. The visit frequency will be once every 4 weeks (Q4W).

Who can join: Review the eligibility criteria below.

Location: Research Site — Palmdale, California

Age range: 12 Years to 80 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (70 Sites)

Showing the first 25 of 70 sites.

Research Site — Palmdale, California
Research Site — Colorado Springs, Colorado
Research Site — Miami, Florida
Research Site — Boston, Massachusetts
Research Site — St Louis, Missouri
Research Site — New Brunswick, New Jersey
Research Site — Oklahoma City, Oklahoma
Research Site — McAllen, Texas
Research Site — Berazategui,
Research Site — CABA,
Research Site — Concepción del Uruguay,
Research Site — Mendoza,
Research Site — Mendoza,
Research Site — Quilmes,
Research Site — Rosario,
Research Site — Rosario,
Research Site — San Miguel de Tucumán,
Research Site — Santa Fe,
Research Site — Anderlecht,
Research Site — Edegem,
Research Site — Erpent,
Research Site — Ghent,
Research Site — Liège,
Research Site — Haskovo,
Research Site — Pleven,

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Severe Asthma

A Long-Term Safety and Efficacy Study of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALOUR) — Bakersfield, California
Using NLP and Neural Networks to Autonomously Identify Severe Asthma and Determine Study Eligibility in a Large Healthcare System — San Diego, California
Tezepelumab in the Treatment of Emergency Room Asthma in Adults (TERAA) — Edmonton, Alberta
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2) — Bakersfield, California
International Severe Asthma Registry: Canadian Cohort — Edmonton, Alberta

Explore by condition: All Severe Asthma clinical trials

💡 How to Participate

Check the checklist above to see if you may qualify.
Review the official NIH record below to find the coordinating site.
Ask about the visit schedule, what is covered at no cost, and any travel support.
Confirm with your own doctor before making a decision.

🏛️ View Official NIH Record ↗