🏛️ Verified NIH Record • Updated 2026-05-12
A Long-Term Safety and Efficacy Study of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALOUR) (NCT06966479)
A Long-Term Extension Study to Evaluate Safety and Efficacy of Verekitug (UPB-101) in Adult Participants With Severe Asthma Who Completed the VALIANT Trial
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Upstream Bio Inc.
🩺 Plain-English Summary (8th-Grade Level)
The primary purpose of this study is to evaluate the long-term safety and efficacy of verekitug (UPB-101) in participants who complete the VALIANT study (NCT06196879).
Who can join: Review the eligibility criteria below.
Location: Kern Research, Inc. — Bakersfield, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (102 Sites)
Showing the first 25 of 102 sites.
- Kern Research, Inc. — Bakersfield, California
- California Medical Research Associates Inc. — Northridge, California
- Integrated Research of Inland Inc — Upland, California
- Allergy & Asthma Clinical Research — Walnut Creek, California
- Allianz Research Institute — Westminster, California
- Advance Pharma Research — Cutler Bay, Florida
- Clinical Site Partners, LLC dba Flourish Research — Miami, Florida
- Phoenix Medical Research — Miami, Florida
- Research Institute of South Florida — Miami, Florida
- Health and Life Research Institute, LLC — Miami, Florida
- Nouvelle Clinical Research — Miami, Florida
- Edward Jenner Research Group, LLC — Plantation, Florida
- R&B Medical Center — Tampa, Florida
- Clinical Site Partners dba Flourish research — Winter Park, Florida
- Treasure Valley Medical Research — Boise, Idaho
- Chesapeake Clinical Research Inc — White Marsh, Maryland
- Pulmonary Research Institute of Southeast Michigan (PRISM) — Farmington Hills, Michigan
- AA MRC — Flint, Michigan
- M3 Wake Research — Las Vegas, Nevada
- Urban Health Plan INC — The Bronx, New York
- Toledo Institute of Clinical Research Inc — Toledo, Ohio
- OK Clinical Research, LLC — Edmond, Oklahoma
- Horizon Clinical Research — Cypress, Texas
- Alina Clinical Trials, LLC — Dallas, Texas
- El Paso Pulmonary Association — El Paso, Texas
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Severe Asthma
- Using NLP and Neural Networks to Autonomously Identify Severe Asthma and Determine Study Eligibility in a Large Healthcare System — San Diego, California
- Open-label Study to Assess Reduction of Background Asthma Medication While Sustaining Asthma Control and Clinical Remission With Tezepelumab in Patients 12-80yrs With Severe Asthma. — Palmdale, California
- Tezepelumab in the Treatment of Emergency Room Asthma in Adults (TERAA) — Edmonton, Alberta
- A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2) — Bakersfield, California
- International Severe Asthma Registry: Canadian Cohort — Edmonton, Alberta
Explore by condition: All Severe Asthma clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.