The APS Phenotyping Study (NCT06521502)
The ARDS, Pneumonia, and Sepsis (APS) Consortium: A Prospective Observational Study to Evaluate Phenotypes
🩺 Plain-English Summary (8th-Grade Level)
The goal of the observational APS phenotyping study is to better understand risk factors, potential biomarkers, length and severity of illness, and recovery for adults with ARDS, pneumonia, and/ or sepsis. This study will also generate a biobank of specimens collected from these patients that will be available to investigators for future studies of ARDS, sepsis, and/or pneumonia.
Who can join: Review the eligibility criteria below.
Location: Fresno Community Hospital and Medical Center — Fresno, California
Age range: 18 Years
🧪 Interventions in This Study
- Blood collection (OTHER)
- Urine Collection (OTHER)
- Nasal, oral, and rectal swabs (OTHER)
- Stool collection (OTHER)
- Heat Moisture Exchange Filter collection (OTHER)
- Tracheal Aspirate sample collection (OTHER)
- Non-bronchoscopic bronchoalveolar lavage (NBBAL) (PROCEDURE)
- Surveys (OTHER)
- Short physical performance battery (OTHER)
- Hand grip strength (OTHER)
- CNS Vital Signs (OTHER)
- Muscle Ultrasound (OTHER)
- Muscle Strength (OTHER)
- Spirometry (OTHER)
- Lung Diffusion Testing (DLCO) (OTHER)
- Chest CT Scan (RADIATION)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (20 Sites)
- Fresno Community Hospital and Medical Center — Fresno, California
- Stanford University — Palo Alto, California
- San Francisco General Hospital — San Francisco, California
- University of California, San Francisco — San Francisco, California
- University of Colorado, Denver — Denver, Colorado
- Denver Health and Hospital Authority — Denver, Colorado
- National Jewish Health — Denver, Colorado
- UC Health Medical Center of the Rockies — Loveland, Colorado
- Northwestern Memorial Hospital — Chicago, Illinois
- University of Chicago — Chicago, Illinois
- Johns Hopkins Univeristy — Baltimore, Maryland
- University of Michigan — Ann Arbor, Michigan
- Washington University School of Medicine — St Louis, Missouri
- Duke University — Durham, North Carolina
- University of Cincinnati — Cincinnati, Ohio
- University of Pennsylvania — Philadelphia, Pennsylvania
- Meharry Medical College — Nashville, Tennessee
- Vanderbilt University Medical Center — Nashville, Tennessee
- Intermountain Medical Center — Murray, Utah
- University of Utah — Salt Lake City, Utah
📞 Contact the Study Coordinator
Phone: (615) 936-8047
Email: wesley.self@vumc.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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Explore by condition: All ARDS clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.