๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-18

Cognitive Training as an Adjunct to Ketamine in Real-world Clinics (NCT06526078)

A Brief Automated Neurocognitive Training to Enhance the Real-World Impact of Ketamine's Rapid Antidepressant Effect

๐ŸŸข Recruiting Observational / Diagnostic ๐Ÿง  Behavioral & Psychological Program Sponsor: University of Pittsburgh

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

In a sample of patients already receiving ketamine (or esketamine) treatment as part of their clinical care, this project seeks to test whether we can enhance and/or extend (es)ketamine's rapid effects by introducing helpful information delivered by a computer-based cognitive training protocol. This work could ultimately lead to the ability to treat depression more efficiently and with broader dissemination by rapidly priming the brain for helpful forms of learning.

Who can join: Review the eligibility criteria below.

Location: Kaiser Foundation Research Institute, a division of Kaiser Foundation Hospitals โ€” Oakland, California

Age range: 18 Years to 80 Years

๐Ÿงช Interventions in This Study

  • Cognitive Training (BEHAVIORAL)
  • Sham Training (BEHAVIORAL)

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (3 Sites)

  • Kaiser Foundation Research Institute, a division of Kaiser Foundation Hospitals โ€” Oakland, California
  • University of Illinois at Chicago โ€” Chicago, Illinois
  • Baylor College of Medicine โ€” Houston, Texas

๐Ÿ“ž Contact the Study Coordinator

Phone: (412) 383-2150

Email: ketclinics@pitt.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Depression clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—