๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-17

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH (NCT06528314)

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

๐ŸŸข Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Akero Therapeutics, Inc

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a multi-center evaluation of efruxifermin (EFX) in a randomized, double-blind, placebo-controlled study in subjects with compensated cirrhosis due to NASH/MASH.

Who can join: Review the eligibility criteria below.

Location: Akero Clinical Study Site โ€” Birmingham, Alabama

Age range: 18 Years to 80 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (329 Sites)

Showing the first 25 of 329 sites.

  • Akero Clinical Study Site โ€” Birmingham, Alabama
  • Akero Clinical Study Site โ€” Dothan, Alabama
  • Akero Clinical Study Site โ€” Chandler, Arizona
  • Akero Clinical Study Site โ€” Flagstaff, Arizona
  • Akero Clinical Study Site โ€” Peoria, Arizona
  • Akero Clinical Study Site โ€” Scottsdale, Arizona
  • Akero Clinical Study Site โ€” Tucson, Arizona
  • Akero Clinical Study Site โ€” Tucson, Arizona
  • Akero Clinical Study Site โ€” Tucson, Arizona
  • Akero Clinical Study Site โ€” Tucson, Arizona
  • Akero Clinical Study Site โ€” Conway, Arkansas
  • Akero Clinical Study Site โ€” Jonesboro, Arkansas
  • Akero Clinical Study Site โ€” Little Rock, Arkansas
  • Akero Clinical Study Site โ€” North Little Rock, Arkansas
  • Akero Clinical Study Site โ€” Coronado, California
  • Akero Clinical Study Site โ€” Escondido, California
  • Akero Clinical Study Site โ€” Folsom, California
  • Akero Clinical Study Site โ€” Fountain Valley, California
  • Akero Clinical Study Site โ€” Lancaster, California
  • Akero Clinical Study Site โ€” Long Beach, California
  • Akero Clinical Study Site โ€” Los Angeles, California
  • Akero Clinical Study Site โ€” Newport Beach, California
  • Akero Clinical Study Site โ€” Orange, California
  • Akero Clinical Study Site โ€” Pasadena, California
  • Akero Clinical Study Site โ€” Redwood City, California

๐Ÿ“ž Contact the Study Coordinator

Phone: (650) 487-6488

Email: AkeroSynchrony@akerotx.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—