A Study of JNJ-64042056 in Participants With Preclinical Alzheimer's Disease (NCT06544616)
A Multicenter, Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study, to Assess Efficacy, Safety and Immunogenicity of JNJ-64042056, a Phosphorylated Tau Targeted Active Immunotherapy, in Participants With Preclinical Alzheimer's Disease
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to assess whether JNJ-64042056 affects the spread and build up of tau (a protein in brain) when compared with placebo, using brain scan (tau PET) to determine results from specific areas of the brain.
Who can join: Review the eligibility criteria below.
Location: Xenoscience Inc. — Phoenix, Arizona
Age range: 55 Years to 75 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (90 Sites)
Showing the first 25 of 90 sites.
- Xenoscience Inc. — Phoenix, Arizona
- Irvine Clinical Research — Irvine, California
- Esperanza Clinical — Murrieta, California
- Artemis Institute for Clinical Research Riverside — Riverside, California
- Artemis Institute for Clinical Research San Diego — San Diego, California
- Yale University School Of Medicine — New Haven, Connecticut
- JEM Research LLC — Atlantis, Florida
- Excel Medical Clinical Trials, LLC — Boca Raton, Florida
- K2 Medical Research Winter Garden — Clermont, Florida
- Clinical NeuroScience Solutions Inc — Jacksonville, Florida
- K2 Medical Research Lady Lake — Lady Lake, Florida
- K2 Medical Research Maitland — Maitland, Florida
- Merritt Island Medical Research, LLC — Merritt Island, Florida
- Headlands Research Orlando — Orlando, Florida
- Alzheimers Research and Treatment Center Stuart — Stuart, Florida
- K2 Medical Research Tampa — Tampa, Florida
- Charter Research — The Villages, Florida
- Alzheimers Research and Treatment Center Wellington — Wellington, Florida
- Palm Beach Neurology and Premier Research Institute — West Palm Beach, Florida
- Great Lakes Clinical Trials Chicago — Chicago, Illinois
- Great Lakes Clinical Trials Gurnee — Gurnee, Illinois
- Quest Research Institute — Farmington Hills, Michigan
- Hattiesburg Clinic — Hattiesburg, Mississippi
- The Cognitive and Research Center of New Jersey LLC — Springfield, New Jersey
- Neurological Associates of Albany, PC — Albany, New York
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.