Quetiapine Versus Trazadone in Women With Postpartum Depression (NCT06546358)
A Pilot, Double-blind, Randomized Trial of Quetiapine Versus Trazadone in Women With Postpartum Depression
🩺 Plain-English Summary (8th-Grade Level)
Postpartum depression is a serious disorder that affects approximately 17% of women who have recently given birth. Untreated postpartum depression can negatively affect the mother, the infant, and the family. Lack of sleep is common after delivery and can trigger or worsen depression in some women. Trazodone is used for sleeplessness and depression, but it has not been studied for postpartum depression. There is preliminary evidence that quetiapine, another drug used for depression and sleeplessness, may be effective for postpartum depression. We are planning a study to compare the effectiveness and side effects of quetiapine and trazodone in women with postpartum depression. The results of this study will help us carry out larger studies comparing these drugs with a placebo (a sugar pill) in postpartum depression. We expect the results of our study will improve the mental health of mothers and the well-being of their babies and make it easier for healthcare staff to select the right drug for women with postpartum depression.
Who can join: Review the eligibility criteria below.
Location: Parkwood Institute — London, Ontario
Age range: 18 Years to 45 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Parkwood Institute — London, Ontario
📞 Contact the Study Coordinator
Phone: (519) 646-6100
Email: vsharma@uwo.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Postpartum Depression
- Preventing Postpartum Depression in Immigrant Latinas — Baltimore, Maryland
- Public Health Nurse-Peer Co-Led Group Cognitive Behavioral Therapy for Postpartum Depression — Hamilton, Ontario
- The Safety, Tolerability, and Effectiveness of Quetiapine in Postpartum Depression — London, Ontario
- The Maternal Well-Being Study — Amarillo, Texas
- CBT for Postpartum Depression and Infant Emotion Regulation — Hamilton, Ontario
- Whole-Body Hyperthermia for Mood and Anxiety Disorders — New York, New York
Explore by condition: All Postpartum Depression clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.