๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-29

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis (NCT06598943)

An Adaptive, Dose-Ranging, Phase 2 Study of Eltrekibart Given Alone or in Combination With Mirikizumab for the Treatment of Adult Patients With Moderately to Severely Active Ulcerative Colitis

๐ŸŸข Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Eli Lilly and Company

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The main purpose of this study is to determine the safety and efficacy of eltrekibart and mirikizumab in adult participants with moderately to severely active ulcerative colitis (UC).

Who can join: Review the eligibility criteria below.

Location: AZ Gastro Care - Chandler โ€” Chandler, Arizona

Age range: 18 Years to 75 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (207 Sites)

Showing the first 25 of 207 sites.

  • AZ Gastro Care - Chandler โ€” Chandler, Arizona
  • Applied Research Center of Arkansas โ€” Little Rock, Arkansas
  • Preferred Research Partners โ€” Little Rock, Arkansas
  • Erick Alayo Medical Corp/Gastro SB Clinic โ€” Chula Vista, California
  • Southern California GI and Liver Centers (SCLC) โ€” Coronado, California
  • Valley View Research โ€” Garden Grove, California
  • Om Research, LLC โ€” Lancaster, California
  • United Medical Doctors โ€” Los Alamitos, California
  • Clinnova Research โ€” Orange, California
  • Prospective Research Innovations โ€” Rancho Cucamonga, California
  • Clinical Trials Management Services, LLC โ€” Thousand Oaks, California
  • Om Research LLC โ€” Victorville, California
  • Peak Gastroenterology Associates โ€” Colorado Springs, Colorado
  • Medical Research Center of Connecticut, LLC โ€” Hamden, Connecticut
  • Novum Research, LLC โ€” Clermont, Florida
  • I.V.A.M. Clinical & Investigational Center, LLC โ€” Doral, Florida
  • Florida Research Institute โ€” Lakewood Rch, Florida
  • Well Pharma Medical Research Corp. โ€” Miami, Florida
  • Reserka โ€” Miami, Florida
  • Digestive Disease Consultants DDCJAX โ€” Orange Park, Florida
  • Orlando Health Digestive Health Institute โ€” Orlando, Florida
  • AdventHealth Orlando โ€” Orlando, Florida
  • Nodal Medical Center โ€” Tampa, Florida
  • Research Bay,Inc. โ€” Tampa, Florida
  • GCP Clinical Research, LLC โ€” Tampa, Florida

๐Ÿ“ž Contact the Study Coordinator

Phone: (317) 615-4559

Email: LillyTrials@Lilly.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—