๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-27

A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers (NCT06663319)

A Phase 1 Study of JNJ-89402638 for Unresectable Metastatic Colorectal Cancer and Other Gastrointestinal Malignancies

๐ŸŸข Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Janssen Research & Development, LLC

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to determine the putative recommended phase 2 dose(s) (RP2Ds) and best way to take (optimal route of administration) JNJ-89402638 and to determine the safety of JNJ-89402638 at the RP2D(s) in participants with metastatic colorectal cancer (mCRC) and metastatic gastric cancer (mGAC) and to determine the safety and tolerability of JNJ-89402638 in combination with bevacizumab or biosimilar with or without chemotherapy in participants with mCRC.

Who can join: Review the eligibility criteria below.

Location: University of Arizona Cancer Center โ€” Tucson, Arizona

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (12 Sites)

  • University of Arizona Cancer Center โ€” Tucson, Arizona
  • University of Colorado Denver Anschultz Medical Campus โ€” Aurora, Colorado
  • Florida Cancer Specialists โ€” Sarasota, Florida
  • Community Health Network โ€” Indianapolis, Indiana
  • Start Midwest โ€” Grand Rapids, Michigan
  • Swedish Cancer Institute โ€” Seattle, Washington
  • Severance Hospital Yonsei University Health System โ€” Seoul,
  • Asan Medical Center โ€” Seoul,
  • Hosp Univ Vall D Hebron โ€” Barcelona,
  • Hosp Univ Fund Jimenez Diaz โ€” Madrid,
  • Hosp. Univ. 12 de Octubre โ€” Madrid,
  • Hosp Univ Hm Sanchinarro โ€” Madrid,

๐Ÿ“ž Contact the Study Coordinator

Phone: (844) 434-4210

Email: Participate-In-This-Study1@its.jnj.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—