๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-09-11

Linking Affective Dynamics in Response to Daily Stress to Peripheral Vascular Function in Working Age Adults (NCT06860724)

๐ŸŸข Recruiting Observational / Diagnostic ๐Ÿ“‹ Clinical Research Protocol Sponsor: University of Delaware

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The objective of this proposal is to determine whether heightened negative affective responsivity (NA-R) to daily stressors is related to blunted nitric oxide (NO)-mediated endothelium-dependent dilation (EDD) in working age adults and the extent to which this association is impacted by major depressive disorder (MDD).

Who can join: Review the eligibility criteria below.

Location: University of Delaware โ€” Newark, Delaware

Age range: 18 Years to 55 Years

๐Ÿงช Interventions in This Study

  • NG-nitro-L-arginine methyl ester (L-NAME) (OTHER)

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (1 Sites)

  • University of Delaware โ€” Newark, Delaware

๐Ÿ“ž Contact the Study Coordinator

Phone: (302) 831-2193

Email: jgreaney@udel.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—