๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-06-23

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007) (NCT06878261)

A Randomised, Double-blind, Placebo-controlled, Parallel Group, Multicentre, Phase III Study to Evaluate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

๐ŸŸข Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: AstraZeneca

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group, Phase 3 Study to Evaluate the Efficacy and Safety of Tezepelumab in Adults with Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD)

Who can join: Review the eligibility criteria below.

Location: Research Site โ€” Cullman, Alabama

Age range: 40 Years to 80 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (268 Sites)

Showing the first 25 of 268 sites.

  • Research Site โ€” Cullman, Alabama
  • Research Site โ€” Phoenix, Arizona
  • Research Site โ€” Scottsdale, Arizona
  • Research Site โ€” Inglewood, California
  • Research Site โ€” Los Angeles, California
  • Research Site โ€” Palo Alto, California
  • Research Site โ€” Redding, California
  • Research Site โ€” San Diego, California
  • Research Site โ€” New Britain, Connecticut
  • Research Site โ€” Wilmington, Delaware
  • Research Site โ€” Bay Pines, Florida
  • Research Site โ€” Boynton Beach, Florida
  • Research Site โ€” Clearwater, Florida
  • Research Site โ€” Fleming Island, Florida
  • Research Site โ€” Jacksonville, Florida
  • Research Site โ€” Leesburg, Florida
  • Research Site โ€” Margate, Florida
  • Research Site โ€” Miami, Florida
  • Research Site โ€” Miami, Florida
  • Research Site โ€” Miami Lakes, Florida
  • Research Site โ€” Ocala, Florida
  • Research Site โ€” Palmetto Bay, Florida
  • Research Site โ€” Winter Park, Florida
  • Research Site โ€” Adairsville, Georgia
  • Research Site โ€” Atlanta, Georgia

๐Ÿ“ž Contact the Study Coordinator

Phone: (877) 240-9479

Email: information.center@astrazeneca.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—