Lipid Infusions to Optimize Nutrition Trial (NCT06915441)
Lipid Infusions to Optimize Nutrition (LION) and Minimize Bronchopulmonary Dysplasia and Neurodevelopmental Impairment in Extremely Preterm Infants: A Randomized Comparative Effectiveness Trial
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to identify survival free of bronchopulmonary dysplasia (BPD), fatty acid profiles, and early biochemical measures for oxidative stress comparing mixed oil lipid emulsion (MOLE) vs soybean oil-based lipid emulsion (SOLE) and to establish whether MOLE or SOLE is more effective in minimizing pulmonary outcomes, neonatal morbidities, long-term morbidity and mortality, and improving discharge growth and Bayley Scales of Infant Development Fourth Edition (BSID-IV) neurodevelopmental assessment at two years
Who can join: Review the eligibility criteria below.
Location: The University of Texas Health Science Center at Houston — Houston, Texas
Age range: 12 Hours to 28 Weeks
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- The University of Texas Health Science Center at Houston — Houston, Texas
📞 Contact the Study Coordinator
Phone: (713) 500-6422
Email: Lindsay.N.Fleig@uth.tmc.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Bronchopulmonary Dysplasia
- Enteral High-dose DHA Supplementation on Bronchopulmonary Dysplasia in Very Preterm Infants: a Collaborative Study — Québec, Quebec
- A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants — Little Rock, Arkansas
- Cellular Therapy for Extreme Preterm Infants at Risk of Developing Bronchopulmonary Dysplasia — Gloucester, Ontario
- Transpyloric Versus Gastric Feeding in Bronchopulmonary Dysplasia — Palo Alto, California
- MRI in BPD Subjects — Cincinnati, Ohio
- Ventilator Pressure and Optimization of Compliance and Hemodynamics — Birmingham, Alabama
Explore by condition: All Bronchopulmonary Dysplasia clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.