๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-02-12

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Immunogenicity of APG777 in Adults With Asthma (NCT06920901)

A Phase 1b, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of APG777 in Adults With Mild-to-Moderate Asthma

๐Ÿ”ต Active, Not Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Apogee Therapeutics, Inc.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a multicenter, randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, PK, and immunogenicity of APG777 in adult participants with mild-to-moderate asthma. The duration of the study will be approximately 52 weeks (364 days) for each participant and will consist of a Screening Period, Treatment Period, and Follow-up Period.

Who can join: Review the eligibility criteria below.

Location: Investigational Site โ€” La Jolla, California

Age range: 18 Years to 65 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (11 Sites)

  • Investigational Site โ€” La Jolla, California
  • Investigational Site โ€” Long Beach, California
  • Investigational Site โ€” San Jose, California
  • Investigational Site โ€” Torrance, California
  • Investigational Site โ€” Normal, Illinois
  • Investigational Site โ€” Kansas City, Missouri
  • Investigational Site โ€” Edmond, Oklahoma
  • Investigational Site โ€” Philadelphia, Pennsylvania
  • Investigational Site โ€” Pittsburgh, Pennsylvania
  • Investigational Site โ€” Bradford, West Yorkshire
  • Investigational Site โ€” Manchester,

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Asthma clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—