ποΈ Verified NIH Record β’ Updated 2026-07-07
Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2) (NCT06958211)
A Phase 3, Double-Blind, Randomized, Vehicle-Controlled, Efficacy and Safety Study of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa
π΅ Active, Not Recruiting Phase3 π Investigational Drug / Biologic Sponsor: Incyte Corporation
π©Ί Plain-English Summary (8th-Grade Level)
The purpose of this study is to evaluate the efficacy and safety of ruxolitinib cream in participants with hidradenitis suppurativa.
Who can join: Review the eligibility criteria below.
Location: Investigative Site US257 β Birmingham, Alabama
Age range: 12 Years
π§ͺ Interventions in This Study
π "Do I Qualify?" β 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria β
π All Participating Trial Locations (107 Sites)
Showing the first 25 of 107 sites.
- Investigative Site US257 β Birmingham, Alabama
- Investigative Site US218 β Birmingham, Alabama
- Investigative Site US239 β Montgomery, Alabama
- Investigative Site US215 β Phoenix, Arizona
- Investigative Site US261 β Phoenix, Arizona
- Investigative Site US240 β Tucson, Arizona
- Investigative Site US262 β Encino, California
- Investigative Site US222 β Fountain Valley, California
- Investigative Site US211 β Los Angeles, California
- Investigative Site US237 β Los Angeles, California
- Investigative Site US234 β Northridge, California
- Investigative Site US250 β Santa Ana, California
- Investigative Site US244 β Castle Rock, Colorado
- Investigative Site US252 β Cromwell, Connecticut
- Investigative Site US208 β Boca Raton, Florida
- Investigative Site US203 β Hialeah, Florida
- Investigative Site US258 β Jacksonville, Florida
- Investigative Site US206 β Maitland, Florida
- Investigative Site US223 β Miami, Florida
- Investigative Site US241 β Miami, Florida
- Investigative Site US202 β Miami, Florida
- Investigative Site US214 β Tampa, Florida
- Investigative Site US247 β Tampa, Florida
- Investigative Site US231 β Columbus, Georgia
- Investigative Site US225 β Sandy Springs, Georgia
π° Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Hidradenitis Suppurativa
- A Study to Assess Disease Activity and Safety of Subcutaneous Lutikizumab (ABT-981) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-Tumor Necrosis Factor (TNF) Therapy and Who Are NaΓ―ve to Biologic Therapy β Phoenix, Arizona
- Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS1) β Phoenix, Arizona
- Study of Single Doses of SBT777101 in Subjects With Hidradenitis Suppurativa β Boston, Massachusetts
- A Study to Assess the Pharmacokinetics and Safety of Bimekizumab in Children and Adolescents With Moderate to Severe Hidradenitis Suppurativa β Phoenix, Arizona
- A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa β Birmingham, Alabama
Explore by condition: All Hidradenitis Suppurativa clinical trials
π‘ How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.